Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35691 | 0.91 | LMNA (0.38) | LMNATDP1ATMHCAR2 | |
| SCHEMBL3791086 | 0.82 | TSHR (0.50) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL3786038 | 0.82 | TSHR (0.50) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL4885631 | 0.81 | TSHR (0.33) | TSHR | |
| SCHEMBL4893048 | 0.81 | TSHR (0.42) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL4888287 | 0.78 | HCAR2 (0.47) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL4888226 | 0.78 | HCAR2 (0.47) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL4889687 | 0.78 | TSHR (0.47) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL440285 | 0.78 | TSHR (0.40) | ALDH1A1TSHRTDP1 | |
| SCHEMBL4895739 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TP53TSHRHIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293872-A1 | ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER | HENKEL AG & CO. KGAA (DE) | 2008-11-27 | — | — | US | disclosed |
| US-20080287574-A1 | ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER | HENKEL AG & CO. KGAA (DE) | 2008-11-20 | — | — | US | disclosed |