Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TYR | P14679 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.40 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200072 | 0.85 | SMN1; SMN2 (0.65) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL4896805 | 0.81 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL453824 | 0.77 | SMN1; SMN2 (1.00) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL3950 | 0.77 | SMN1; SMN2 (1.00) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL3858830 | 0.77 | SMN1; SMN2 (0.65) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL1642851 | 0.76 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL1374664 | 0.76 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL7075597 | 0.75 | SMN1; SMN2 (0.95) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL11857289 | 0.75 | SMN1; SMN2 (0.95) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL11859223 | 0.75 | SMN1; SMN2 (0.95) | ALDH1A1SMN1; SMN2CA2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255240-A1 | Sulfonamide Derivatives | NOVO NORDISK A/S (DK) | 2008-10-16 | — | — | US | disclosed |
| EP-1756025-A1 | SULFONAMIDE DERIVATIVES | NOVO NORDISK A/S (DK) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005105712-A1 | SULFONAMIDE DERIVATIVES | NOVO NORDISK A/S (DK) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255240-A1 | Sulfonamide Derivatives | FABP4, SQOR, CS | ALDH1A1 1601/4885SMN1; SMN2 2304/4885CA2 1064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.