Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.40 |
| ▸ | GSR | P00390 | 2/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4893529 | 1.00 | SLC1A5 (0.43) | SLC1A5NOS3NOS1NOS2IDO1 | |
| SCHEMBL21973559 | 0.84 | SLC1A1 (0.44) | SLC1A5NOS3NOS1NOS2IDO1 | |
| SCHEMBL352049 | 0.82 | SLC1A5 (0.43) | SLC1A5NOS3NOS1NOS2IDO1 | |
| SCHEMBL3502798 | 0.82 | SLC1A5 (0.43) | SLC1A5NOS3NOS1NOS2IDO1 | |
| SCHEMBL6424789 | 0.80 | TRPA1 (0.43) | SLC1A5NOS3NOS1NOS2IDO1 | |
| SCHEMBL6424791 | 0.80 | TRPA1 (0.43) | SLC1A5NOS3NOS1NOS2IDO1 | |
| SCHEMBL2507780 | 0.80 | NOS1 (0.44) | SLC1A5NOS3NOS1NOS2IDO1 | |
| SCHEMBL21531604 | 0.80 | SLC1A5 (0.42) | SLC1A5NOS3NOS1NOS2IDO1 | |
| SCHEMBL1526149 | 0.80 | PTGS1 (0.50) | SLC1A5NOS3NOS1NOS2IDO1 | |
| SCHEMBL28884046 | 0.80 | NOS1 (0.44) | SLC1A5NOS3NOS1NOS2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402407-B1 | Chemically targeted positional identification of post-translationally phosphorylated peptides | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-07-22 | — | — | US | disclosed |
| EP-0472220-A1 | Bradykinin antagonists | SYNTEX (U.S.A.) INC. (US) | 1992-02-26 | — | — | EP | disclosed |
| US-5091367-A | Fertility agents, antifertility agents, hormone inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| US-4861755-A | Peptides with vasorelaxant, natriuretic and diuretic effects a process for their preparation, agents containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-29 | — | — | US | disclosed |