SCHEMBL21531604

SCHEMBL21531604

N[C@@H](COC(=O)CC(=O)O)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A5 Q15758 1/20 0.42
SLC1A1 P43005 3/20 0.41
GSR P00390 2/20 0.41
GRIK1 P39086 2/20 0.41
GRIK2 Q13002 2/20 0.41
GRM1 Q13255 2/20 0.41
GRM2 Q14416 2/20 0.41
GRM8 O00222 1/20 0.41
GRM6 O15303 1/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
CYP1A2 P05177 1/20 0.41
GRM5 P41594 1/20 0.41
GRIA1 P42261 1/20 0.41
GRIA2 P42262 1/20 0.41
GRIA3 P42263 1/20 0.41
SLC1A3 P43003 1/20 0.41
SLC1A2 P43004 1/20 0.41
GRIA4 P48058 1/20 0.41
GRIN1 Q05586 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8234920 0.83 NOS3 (0.46) SLC1A5SLC1A1GRIK1SLC1A3SLC1A2
SCHEMBL21531603 0.83 NOS3 (0.46) SLC1A5SLC1A1GRIK1SLC1A3SLC1A2
SCHEMBL21973559 0.82 SLC1A1 (0.44) SLC1A5SLC1A1GSRGRIK1GRIK2
SCHEMBL7991509 0.81 GRM8 (0.50) SLC1A5SLC1A1GSRGRIK1GRIK2
Glycine SCHEMBL8588130 0.81 GLRA1 (0.42) SLC1A5SLC1A1GSRGRIK1GRIK2
SCHEMBL4893526 0.80 SLC1A5 (0.43) SLC1A5SLC1A1GSRGRIK1GRIK2
SCHEMBL352049 0.80 SLC1A5 (0.43) SLC1A5SLC1A1GSRGRIK1GRIK2
SCHEMBL4893529 0.80 SLC1A5 (0.43) SLC1A5SLC1A1GSRGRIK1GRIK2
SCHEMBL3502798 0.80 SLC1A5 (0.43) SLC1A5SLC1A1GSRGRIK1GRIK2
SCHEMBL21531606 0.79 SLC1A1 (0.48) SLC1A1GSRGRIK1GRIK2GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3562950-B1 PROCESS FOR THE SYNTHESIS OF FUNCTIONALIZED CYCLIC DITHIOCARBAMATES ARKEMA FRANCE (FR) 2024-10-02 EP claimed
CN-110100004-B Synthesis of functionalized cyclic dithiocarbamic acid or ester 阿肯马法国公司 2023-09-19 CN claimed
US-20230159967-A1 FUNCTIONALISED POLSULPHIDE SYNTHESIS METHOD ARKEMA FRANCE (FR) 2023-05-25 US claimed
US-11643673-B2 Functionalised cyclic dithiocarbamate synthesis method ARKEMA FRANCE (FR) 2023-05-09 US claimed
US-20200149080-A1 FUNCTIONALISED CYCLIC DITHIOCARBAMATE SYNTHESIS METHOD ARKEMA FRANCE (FR) 2020-05-14 US claimed
US-20190338325-A1 FUNCTIONALISED POLYSULPHIDE SYNTHESIS METHOD ARKEMA FRANCE (FR) 2019-11-07 US claimed
EP-3562950-B1 PROCESS FOR THE SYNTHESIS OF FUNCTIONALIZED CYCLIC DITHIOCARBAMATES ARKEMA FRANCE (FR) 2024-10-02 EP disclosed
US-20240002893-A1 PROCESS FOR SYNTHESIZING FUNCTIONALIZED MERCAPTANS UNDER AN H2S PRESSURE ARKEMA FRANCE (FR) 2024-01-04 US disclosed
EP-4255887-A1 METHOD FOR SYNTHESISING FUNCTIONALISED MERCAPTANS UNDER H2S PRESSURE ARKEMA FRANCE (FR) 2023-10-11 EP disclosed
US-20230295080-A1 IMPROVED PROCESS FOR SYNTHESIZING FUNCTIONALIZED MERCAPTANS ARKEMA FRANCE (FR) 2023-09-21 US disclosed
CN-110100004-B Synthesis of functionalized cyclic dithiocarbamic acid or ester 阿肯马法国公司 2023-09-19 CN disclosed
CN-116601143-A For at H 2 Method for synthesizing functionalized mercaptan under S pressure 阿科玛法国公司 2023-08-15 CN disclosed
US-20230159967-A1 FUNCTIONALISED POLSULPHIDE SYNTHESIS METHOD ARKEMA FRANCE (FR) 2023-05-25 US disclosed
EP-4182300-A1 IMPROVED METHOD FOR SYNTHESISING FUNCTIONALISED MERCAPTANS ARKEMA FRANCE (FR) 2023-05-24 EP disclosed
US-11643673-B2 Functionalised cyclic dithiocarbamate synthesis method ARKEMA FRANCE (FR) 2023-05-09 US disclosed
US-11578345-B2 Functionalised polysulphide synthesis method ARKEMA FRANCE (FR) 2023-02-14 US disclosed
WO-2022117951-A1 METHOD FOR SYNTHESISING FUNCTIONALISED MERCAPTANS UNDER H2S PRESSURE ARKEMA FRANCE (FR) 2022-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11578345-B2 Functionalised polysulphide synthesis method STS, PFAS, SCLY SLC1A5 3268/4885SLC1A1 3786/4885GSR 412/4885
US-11643673-B2 Functionalised cyclic dithiocarbamate synthesis method TST, DTYMK, DDO SLC1A5 3093/4885SLC1A1 3113/4885GSR 633/4885
US-20190338325-A1 FUNCTIONALISED POLYSULPHIDE SYNTHESIS METHOD STS, PFAS, SCLY SLC1A5 3268/4885SLC1A1 3786/4885GSR 412/4885
US-20200149080-A1 FUNCTIONALISED CYCLIC DITHIOCARBAMATE SYNTHESIS METHOD TST, DTYMK, DDO SLC1A5 3093/4885SLC1A1 3113/4885GSR 633/4885
US-20230159967-A1 FUNCTIONALISED POLSULPHIDE SYNTHESIS METHOD POLH, POLD1, POLR2H SLC1A5 4417/4885SLC1A1 4190/4885GSR 1179/4885
US-20230295080-A1 IMPROVED PROCESS FOR SYNTHESIZING FUNCTIONALIZED MERCAPTANS CBR3, RTN3, OR10J3 SLC1A5 1066/4885SLC1A1 1643/4885GSR 1325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.