SCHEMBL2507780

SCHEMBL2507780

CCC(=O)OC[C@H](N)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.44
NOS3 P29474 1/20 0.44
NOS2 P35228 1/20 0.44
GRIK1 P39086 2/20 0.42
GRIA4 P48058 1/20 0.42
GRIK3 Q13003 1/20 0.42
GRIK5 Q16478 1/20 0.42
P2RY10 O00398 7/20 0.42
GPR34 Q9UPC5 4/20 0.42
GPR174 Q9BXC1 3/20 0.42
SLC1A5 Q15758 1/20 0.42
SLC1A1 P43005 4/20 0.42
SLC1A3 P43003 3/20 0.42
SLC1A2 P43004 3/20 0.42
SLC7A5 Q01650 1/20 0.41
IDO1 P14902 1/20 0.40
GRIK2 Q13002 1/20 0.39
PTGS1 P23219 1/20 0.39
SLC7A11 Q9UPY5 1/20 0.39
DDAH1 O94760 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28884046 1.00 NOS1 (0.44) NOS1NOS3NOS2GRIK1GRIA4
SCHEMBL2507427 0.83 P2RY10 (0.50) NOS1NOS3NOS2P2RY10GPR34
SCHEMBL27139244 0.83 P2RY10 (0.50) NOS1NOS3NOS2P2RY10GPR34
SCHEMBL27872416 0.83 NAAA (0.38) NOS1NOS3NOS2P2RY10GPR34
SCHEMBL21973559 0.82 SLC1A1 (0.44) NOS1NOS3NOS2GRIK1GRIA4
SCHEMBL4893529 0.80 SLC1A5 (0.43) NOS1NOS3NOS2GRIK1GRIA4
SCHEMBL3502798 0.80 SLC1A5 (0.43) NOS1NOS3NOS2GRIK1GRIA4
SCHEMBL4893526 0.80 SLC1A5 (0.43) NOS1NOS3NOS2GRIK1GRIA4
SCHEMBL352049 0.80 SLC1A5 (0.43) NOS1NOS3NOS2GRIK1GRIA4
SCHEMBL6668936 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3562950-B1 PROCESS FOR THE SYNTHESIS OF FUNCTIONALIZED CYCLIC DITHIOCARBAMATES ARKEMA FRANCE (FR) 2024-10-02 EP claimed
US-20230159967-A1 FUNCTIONALISED POLSULPHIDE SYNTHESIS METHOD ARKEMA FRANCE (FR) 2023-05-25 US claimed
US-11643673-B2 Functionalised cyclic dithiocarbamate synthesis method ARKEMA FRANCE (FR) 2023-05-09 US claimed
US-8518989-B2 Prodrugs of short-chain fatty acids and treatment methods GEORGIA HEALTH SCIENCES UNIVERSITY RESEARCH INSTITUTE, INC. (US) 2013-08-27 US claimed
US-20110245339-A1 PRODRUGS OF SHORT-CHAIN FATTY ACIDS AND TREATMENT METHODS MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC (US) 2011-10-06 US claimed
US-20090123388-A1 Prodrugs of Short-Chain Fatty Acids and Treatment Methods MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE (US) 2009-05-14 US claimed
WO-2006076734-A2 PRODRUGS OF SHORT-CHAIN FATTY ACIDS AND TREATMENT METHODS MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE (US) 2006-07-20 WO claimed
EP-3562950-B1 PROCESS FOR THE SYNTHESIS OF FUNCTIONALIZED CYCLIC DITHIOCARBAMATES ARKEMA FRANCE (FR) 2024-10-02 EP disclosed
US-20240002893-A1 PROCESS FOR SYNTHESIZING FUNCTIONALIZED MERCAPTANS UNDER AN H2S PRESSURE ARKEMA FRANCE (FR) 2024-01-04 US disclosed
EP-4255887-A1 METHOD FOR SYNTHESISING FUNCTIONALISED MERCAPTANS UNDER H2S PRESSURE ARKEMA FRANCE (FR) 2023-10-11 EP disclosed
US-20230295080-A1 IMPROVED PROCESS FOR SYNTHESIZING FUNCTIONALIZED MERCAPTANS ARKEMA FRANCE (FR) 2023-09-21 US disclosed
CN-110100004-B Synthesis of functionalized cyclic dithiocarbamic acid or ester 阿肯马法国公司 2023-09-19 CN disclosed
CN-116601143-A For at H 2 Method for synthesizing functionalized mercaptan under S pressure 阿科玛法国公司 2023-08-15 CN disclosed
US-9096642-B2 Therapeutic compounds for immunomodulation AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) 2015-08-04 US disclosed
US-20140199334-A1 Therapeutic Compounds for Immunomodulation AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) 2014-07-17 US disclosed
US-8518989-B2 Prodrugs of short-chain fatty acids and treatment methods GEORGIA HEALTH SCIENCES UNIVERSITY RESEARCH INSTITUTE, INC. (US) 2013-08-27 US disclosed
US-20110245339-A1 PRODRUGS OF SHORT-CHAIN FATTY ACIDS AND TREATMENT METHODS MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC (US) 2011-10-06 US disclosed
US-20090123388-A1 Prodrugs of Short-Chain Fatty Acids and Treatment Methods MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE (US) 2009-05-14 US disclosed
US-20090123388-A1 Prodrugs of Short-Chain Fatty Acids and Treatment Methods MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE (US) 2009-05-14 US disclosed
WO-2006076734-A2 PRODRUGS OF SHORT-CHAIN FATTY ACIDS AND TREATMENT METHODS MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE (US) 2006-07-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11643673-B2 Functionalised cyclic dithiocarbamate synthesis method TST, DTYMK, DDO NOS1 1299/4885NOS3 1136/4885NOS2 803/4885
US-20090123388-A1 Prodrugs of Short-Chain Fatty Acids and Treatment Methods SLC1A5, SPTSSB, SLC27A1 NOS1 902/4885NOS3 836/4885NOS2 840/4885
US-20110245339-A1 PRODRUGS OF SHORT-CHAIN FATTY ACIDS AND TREATMENT METHODS SLC1A5, SPTSSB, SLC27A1 NOS1 902/4885NOS3 836/4885NOS2 840/4885
US-20230159967-A1 FUNCTIONALISED POLSULPHIDE SYNTHESIS METHOD POLH, POLD1, POLR2H NOS1 2674/4885NOS3 2744/4885NOS2 2232/4885
US-20140199334-A1 Therapeutic Compounds for Immunomodulation CD274, PDCD1, PDCD1LG2 NOS1 1848/4885NOS3 2700/4885NOS2 2179/4885
US-20230295080-A1 IMPROVED PROCESS FOR SYNTHESIZING FUNCTIONALIZED MERCAPTANS CBR3, RTN3, OR10J3 NOS1 547/4885NOS3 52/4885NOS2 559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.