Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 8/20 | 0.47 |
| ▸ | MMP2 | P08253 | 7/20 | 0.47 |
| ▸ | MMP14 | P50281 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4893850 | 0.87 | PLA2G2A (0.46) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL4887465 | 0.87 | AR (0.50) | HRH3MMP13MMP2MMP14KDM4E | |
| SCHEMBL4886339 | 0.85 | PLA2G2A (0.55) | KDM4ELMNASMN1; SMN2GAAMAPT | |
| SCHEMBL4893009 | 0.83 | PLA2G2A (0.51) | KDM4ELMNAGAAMAPTKMT2A | |
| SCHEMBL4887373 | 0.81 | SERPINE1 (0.55) | KDM4ELMNAGAAMAPTKMT2A | |
| SCHEMBL5415705 | 0.74 | MAPK8 (0.52) | KDM4EALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL656018 | 0.74 | KDM4E (0.74) | HRH3MMP13MMP2MMP14KDM4E | |
| SCHEMBL4887461 | 0.74 | AR (0.51) | KDM4ELMNAGAAMAPTMEN1 | |
| SCHEMBL419130 | 0.73 | MMP13 (0.77) | HRH3MMP13MMP2MMP14KDM4E | |
| Hydrochloric Acid SCHEMBL28674698 | 0.73 | KDM4E (0.72) | HRH3MMP13MMP2MMP14KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319046-A1 | SUBSTITUTED SULFONAMIDE-INDOLES | WYETH (US) | 2008-12-25 | — | — | US | disclosed |
| US-7442805-B2 | Substituted sulfonamide-indoles | WYETH (US) | 2008-10-28 | — | — | US | disclosed |
| US-20050096377-A1 | Substituted sulfonamide-indoles | WYETH (US) | 2005-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319046-A1 | SUBSTITUTED SULFONAMIDE-INDOLES | STS, TPST2, IDO2 | HRH3 988/4885MMP13 4225/4885MMP2 4537/4885 |
| US-20050096377-A1 | Substituted sulfonamide-indoles | STS, TPST2, IDO2 | HRH3 988/4885MMP13 4225/4885MMP2 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.