Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GRM5 | P41594 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894867 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GRM5TSHRCHRNA4SCD5 | |
| SCHEMBL17327488 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TSHRCHRNA4HPGDKMT2A | |
| SCHEMBL3094697 | 0.79 | NPC1 (0.53) | ALDH1A1 | |
| SCHEMBL10232967 | 0.78 | CHRNA4 (0.44) | GRM5CHRNA4SCD5KMT2AGAA | |
| SCHEMBL3337107 | 0.76 | CHRNA4 (0.48) | GRM5CHRNA4SCD5SCDKMT2A | |
| SCHEMBL4892496 | 0.76 | ALDH1A1 (0.53) | ALDH1A1 | |
| SCHEMBL4892492 | 0.76 | ALDH1A1 (0.53) | ALDH1A1 | |
| SCHEMBL3339919 | 0.76 | CHRNA4 (0.44) | GRM5CHRNA4SCD5SCDKMT2A | |
| SCHEMBL3330947 | 0.76 | CHRNA4 (0.60) | GRM5CHRNA4SCD5SCDKMT2A | |
| SCHEMBL18135148 | 0.76 | SCD5 (0.67) | GRM5SCD5SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | SSU72, POLR2H, POLR2E | ALDH1A1 276/4885GRM5 3835/4885TSHR 2909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.