Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892496 | 1.00 | ALDH1A1 (0.53) | ALDH1A1DGAT1CA2SMN1; SMN2ACE | |
| SCHEMBL4894867 | 0.76 | ALDH1A1 (0.49) | ALDH1A1 | |
| SCHEMBL4894873 | 0.76 | ALDH1A1 (0.49) | ALDH1A1 | |
| SCHEMBL6787964 | 0.75 | ALDH1A1 (0.52) | ALDH1A1DGAT1CA2SMN1; SMN2L3MBTL1 | |
| SCHEMBL6787956 | 0.75 | ALDH1A1 (0.52) | ALDH1A1DGAT1CA2SMN1; SMN2L3MBTL1 | |
| SCHEMBL20254703 | 0.72 | DGAT1 (0.58) | ALDH1A1DGAT1CA2SMN1; SMN2L3MBTL1 | |
| SCHEMBL20254517 | 0.72 | DGAT1 (0.58) | ALDH1A1DGAT1CA2L3MBTL1 | |
| SCHEMBL6787910 | 0.72 | CA2 (0.75) | ALDH1A1CA2SMN1; SMN2L3MBTL1 | |
| SCHEMBL5537767 | 0.72 | CA2 (0.75) | ALDH1A1CA2SMN1; SMN2L3MBTL1 | |
| SCHEMBL4887329 | 0.71 | CA2 (0.48) | ALDH1A1DGAT1CA2SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | SSU72, POLR2H, POLR2E | ALDH1A1 276/4885DGAT1 1581/4885CA2 1113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.