Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 12/20 | 0.58 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.58 |
| ▸ | OXTR | P30559 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4895457 | 0.97 | LMNA (0.56) | AVPR2AVPR1ALMNATSHRALDH1A1 | |
| SCHEMBL4902129 | 0.82 | POLB (0.48) | LMNASLC22A12ALDH1A1HPGD | |
| SCHEMBL4895551 | 0.81 | BRD4 (0.52) | LMNASLC22A12ALDH1A1HPGD | |
| SCHEMBL4901495 | 0.81 | POLB (0.50) | AVPR2TSHRALDH1A1 | |
| SCHEMBL4899486 | 0.81 | GPBAR1 (0.48) | LMNASLC22A12HPGD | |
| SCHEMBL4895521 | 0.81 | AVPR2 (0.70) | AVPR2AVPR1AOXTRTSHRSLC22A12 | |
| SCHEMBL4898058 | 0.80 | AVPR1A (0.44) | AVPR2AVPR1ASLC22A12ALDH1A1 | |
| SCHEMBL4898923 | 0.79 | DRD4 (0.49) | LMNASLC22A12ALDH1A1 | |
| SCHEMBL12753240 | 0.79 | POLB (0.56) | AVPR2AVPR1ALMNATSHRALDH1A1 | |
| SCHEMBL4900137 | 0.79 | GAA (0.47) | LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080305169-A1 | Pharmaceutical Compositions Comprising Nitrogen-Containing Fused Ring Coumpounds | JAPAN TOBACCO INC. (JP) | 2008-12-11 | — | — | US | disclosed |
| US-20080064871-A1 | Production Method of Nitrogen-Containing Fused Ring Compounds | JAPAN TOBACCO INC. (JP) | 2008-03-13 | — | — | US | disclosed |
| EP-1820515-A1 | NITROGEN-CONTAINING FUSED RING COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2007-08-22 | — | — | EP | disclosed |
| US-20070010670-A1 | Nitrogen-containing fused ring compounds and use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080305169-A1 | Pharmaceutical Compositions Comprising Nitrogen-Containing Fused Ring Coumpounds | NOD1, NLRP3, SLC10A1 | AVPR2 2370/4885AVPR1A 3879/4885OXTR 3337/4885 |
| US-20070010670-A1 | Nitrogen-containing fused ring compounds and use thereof | NUDT1, NOD1, SLC28A1 | AVPR2 4216/4885AVPR1A 4230/4885OXTR 2938/4885 |
| US-20080064871-A1 | Production Method of Nitrogen-Containing Fused Ring Compounds | NOD1, XDH, URB2 | AVPR2 2871/4885AVPR1A 4032/4885OXTR 3962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.