Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 7/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 6/20 | 0.33 |
| ▸ | HTR2B | P41595 | 5/20 | 0.33 |
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR5A | P47898 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR1E | P28566 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12004944 | 0.77 | TAAR1 (0.37) | TAAR1HTR2AHRH3HTR2CHTR2B | |
| SCHEMBL9688847 | 0.76 | TAAR1 (0.41) | TAAR1HTR2AHRH3HTR2CHTR2B | |
| SCHEMBL9540845 | 0.72 | HRH3 (0.36) | TAAR1HTR2AHRH3HTR2CHTR2B | |
| SCHEMBL9688670 | 0.71 | AOC3 (0.50) | HTR2AHTR6HTR1A | |
| SCHEMBL11908240 | 0.71 | HRH3 (0.39) | TAAR1HRH3HTR7 | |
| SCHEMBL23089612 | 0.70 | NOS1 (0.41) | TAAR1HTR2AHRH3HTR2CHTR1A | |
| SCHEMBL1264457 | 0.69 | NOS1 (0.33) | — | |
| SCHEMBL10425883 | 0.69 | G6PD (0.41) | TAAR1HTR2AHRH3HTR2CHTR2B | |
| SCHEMBL4710713 | 0.68 | HTR2A (0.51) | TAAR1HTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL29229089 | 0.68 | TAAR1 (0.37) | TAAR1HTR2AHRH3HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214562-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214562-A1 | Chemical Compounds | CCR5, CXCR4, CXCR3 | TAAR1 2042/4885HTR2A 3458/4885HRH3 782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.