SCHEMBL4895702

SCHEMBL4895702

c1ccc(-c2ccc3c(c2)-c2cc(-c4ccccc4)ccc2C3)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYRO3 Q06418 1/20 0.53
NTRK2 Q16620 1/20 0.53
CLK4 Q9HAZ1 1/20 0.53
DYRK1B Q9Y463 1/20 0.53
TDP2 O95551 6/20 0.52
NPC1 O15118 4/20 0.47
MAPT P10636 4/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
LMNA P02545 2/20 0.47
RAB9A P51151 2/20 0.47
APAF1 O14727 1/20 0.47
THRB P10828 1/20 0.47
XBP1 P17861 1/20 0.47
PTBP1 P26599 1/20 0.47
HTT P42858 1/20 0.47
GALK1 P51570 1/20 0.47
BLM P54132 1/20 0.47
SMAD3 P84022 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29785060 1.00 TYRO3 (0.53) TYRO3NTRK2CLK4DYRK1BTDP2
SCHEMBL27614921 0.94 NPC1 (0.52) TYRO3NTRK2CLK4DYRK1BTDP2
SCHEMBL12192630 0.88 TYRO3 (0.45) TYRO3NTRK2CLK4DYRK1BTDP2
SCHEMBL7139324 0.86 TDP2 (0.58) TYRO3NTRK2CLK4DYRK1BTDP2
SCHEMBL23581451 0.86 ALDH1A1 (0.57) NPC1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL29569358 0.86 TDP2 (0.61) TYRO3NTRK2CLK4DYRK1BTDP2
SCHEMBL3136254 0.86 TDP2 (0.61) TYRO3NTRK2CLK4DYRK1BTDP2
SCHEMBL1482920 0.86 TDP2 (0.61) TYRO3NTRK2CLK4DYRK1BTDP2
SCHEMBL19368548 0.85 CYP19A1 (0.46) TYRO3NTRK2CLK4DYRK1BTDP2
SCHEMBL19368666 0.85 CYP19A1 (0.46) TYRO3NTRK2CLK4DYRK1BTDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250136738-A1 CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, AND OPTICAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2025-05-01 US claimed
EP-4501992-A1 CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, AND OPTICAL MATERIAL Mitsui Chemicals, Inc. (JP) 2025-02-05 EP claimed
WO-2023188978-A1 CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, AND OPTICAL MATERIAL 三井化学株式会社 2023-10-05 WO claimed
US-20250136738-A1 CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, AND OPTICAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2025-05-01 US disclosed
US-20250115689-A1 POLYFUNCTIONAL (METH)ACRYLATE THIOESTER COMPOSITION, CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, OPTICAL MATERIAL, AND METHOD FOR PRODUCING POLYFUNCTIONAL (METH)ACRYLATE THIOESTER COMPOSITION MITSUI CHEMICALS, INC. (JP) 2025-04-10 US disclosed
EP-4501992-A1 CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, AND OPTICAL MATERIAL Mitsui Chemicals, Inc. (JP) 2025-02-05 EP disclosed
EP-4501978-A1 POLYFUNCTIONAL (METH)ACRYLATE THIOESTER COMPOSITION, CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, OPTICAL MATERIAL, AND METHOD FOR PRODUCING POLYFUNCTIONAL (METH)ACRYLATE THIOESTER COMPOSITION Mitsui Chemicals, Inc. (JP) 2025-02-05 EP disclosed
US-20250011590-A1 OPTICAL FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2025-01-09 US disclosed
EP-4431989-A1 OPTICAL FILM AND POLARIZING PLATE Tosoh Corporation (JP) 2024-09-18 EP disclosed
CN-118235072-A Optical film and polarizing plate 东曹株式会社 2024-06-21 CN disclosed
WO-2023188968-A1 POLYFUNCTIONAL (METH)ACRYLATE THIOESTER COMPOSITION, CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, OPTICAL MATERIAL, AND METHOD FOR PRODUCING POLYFUNCTIONAL (METH)ACRYLATE THIOESTER COMPOSITION 三井化学株式会社 2023-10-05 WO disclosed
WO-2023188978-A1 CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, AND OPTICAL MATERIAL 三井化学株式会社 2023-10-05 WO disclosed
WO-2023090353-A1 OPTICAL FILM AND POLARIZING PLATE 東ソー株式会社 2023-05-25 WO disclosed
US-20230091908-A1 FLUORENE DERIVATIVE, METHOD FOR PRODUCING SAME, AND APPLICATION OF SAME OSAKA GAS CHEMICALS CO., LTD. (JP) 2023-03-23 US disclosed
US-8084559-B2 Ethylene-vinylcyclohexane copolymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-27 US disclosed
US-20080161514-A1 Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer SUMITOMO CHEMICAL COMPANY, LIMTIED (JP) 2008-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230091908-A1 FLUORENE DERIVATIVE, METHOD FOR PRODUCING SAME, AND APPLICATION OF SAME ADORA2B, ADORA2A, ADORA1 TYRO3 1471/4885NTRK2 810/4885CLK4 2709/4885
US-20080161514-A1 Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer AOC2, ACSL1, ACSL3 TYRO3 2493/4885NTRK2 3861/4885CLK4 3442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.