Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 8/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892082 | 0.78 | MAPT (0.47) | L3MBTL1HTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL4886948 | 0.74 | TSHR (0.53) | L3MBTL1HTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL4892866 | 0.73 | SMN1; SMN2 (0.46) | L3MBTL1HTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL4508777 | 0.70 | L3MBTL1 (0.66) | L3MBTL1HTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL4789183 | 0.70 | NPC1 (0.49) | L3MBTL1HTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL3288928 | 0.69 | L3MBTL1 (0.46) | L3MBTL1HTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL11013240 | 0.68 | HPGD (0.75) | L3MBTL1HTTALDH1A1KDM4EHPGD | |
| SCHEMBL4896089 | 0.68 | L3MBTL1 (0.46) | L3MBTL1HTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL4892548 | 0.68 | MAPT (0.47) | L3MBTL1HTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL3441603 | 0.68 | L3MBTL1 (0.48) | L3MBTL1HTTNPSR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312305-A1 | Imidazoles as Gaba- B Receptor Modulators | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | claimed |
| US-20080312305-A1 | Imidazoles as Gaba- B Receptor Modulators | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | disclosed |
| US-20080312305-A1 | Imidazoles as Gaba- B Receptor Modulators | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | disclosed |
| US-20080312305-A1 | Imidazoles as Gaba- B Receptor Modulators | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312305-A1 | Imidazoles as Gaba- B Receptor Modulators | GABRB1, GABBR2, GABRB2 | L3MBTL1 2853/4885HTT 4375/4885NPSR1 66/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.