Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.75 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.75 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.75 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.75 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.75 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.75 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.75 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.68 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.68 |
| ▸ | F13A1 | P00488 | 1/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13073336 | 0.94 | HDAC3 (0.71) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL3825861 | 0.89 | HDAC3 (0.68) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL30683377 | 0.88 | HDAC1 (0.66) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL7441298 | 0.87 | HDAC3 (0.79) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL7441870 | 0.87 | HDAC3 (0.79) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL10436247 | 0.87 | HDAC3 (0.74) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL7436977 | 0.87 | HDAC3 (0.79) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| Hydrochloric Acid SCHEMBL27811541 | 0.87 | HDAC3 (0.66) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL17117356 | 0.87 | HDAC1 (0.79) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL4074353 | 0.87 | HDAC3 (0.87) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402673-B2 | Diamine β2 adrenergic receptor agonists | THERAVANCE, INC. (US) | 2008-07-22 | — | — | US | disclosed |
| US-20080039495-A1 | Diamine Beta2 Adrenergic Receptor Agonists | THERAVANCE BIOPHARMA R&D IP, LLC | 2008-02-14 | — | — | US | disclosed |
| EP-1751086-A2 | DIAMINE ß2 ADRENERGIC RECEPTOR AGONISTS | Theravance, Inc. (US) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005121065-A2 | DIAMINE β2 ADRENERGIC RECEPTOR AGONISTS | THERAVANCE, INC. (US) | 2005-12-22 | — | — | WO | disclosed |
| US-20050272769-A1 | Diamine beta2 adrenergic receptor agonists | THERAVANCE, INC. (US) | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272769-A1 | Diamine beta2 adrenergic receptor agonists | ADRB2, ADRB1, ADRA2C | HDAC3 4238/4885HDAC1 4619/4885HDAC2 1941/4885 |
| US-20080039495-A1 | Diamine Beta2 Adrenergic Receptor Agonists | ADRB2, ADRB1, ADRA2C | HDAC3 4238/4885HDAC1 4619/4885HDAC2 1941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.