Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858 | 0.88 | KDM4E (0.50) | G6PDCASP7CASP6HMGB1KDM4E | |
| SCHEMBL289432 | 0.79 | KAT8 (0.50) | G6PDCASP7CASP6HMGB1KDM4E | |
| Salicylic Acid SCHEMBL9718913 | 0.78 | ALDH1A1 (0.67) | G6PDCASP7CASP6HMGB1KDM4E | |
| SCHEMBL3391070 | 0.78 | ALDH1A1 (0.48) | HMGB1KDM4ECA12ALDH1A1HPGD | |
| SCHEMBL4473539 | 0.77 | KAT8 (0.56) | KDM4EALDH1A1MCL1BIDBCL2L1 | |
| Acetic Acid SCHEMBL28668088 | 0.76 | JUN (0.46) | CA12ALDH1A1CA1CA2CA7 | |
| SCHEMBL2821516 | 0.76 | KAT8 (0.59) | KDM4EALDH1A1MCL1BIDBCL2L1 | |
| SCHEMBL5271556 | 0.76 | KAT8 (0.59) | KDM4EALDH1A1MCL1BIDBCL2L1 | |
| SCHEMBL5273325 | 0.76 | KAT8 (0.59) | KDM4EALDH1A1MCL1BIDBCL2L1 | |
| SCHEMBL6434109 | 0.76 | KAT8 (0.59) | KDM4EALDH1A1MCL1BIDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080193377-A1 | Radiolabeled Nanohybrids Targeting Solid Tumor Neovasculature and Method of Using Same | UNIVERSITY OF MARYLAND, BALTIMORE | 2008-08-14 | — | — | US | disclosed |
| EP-1768706-A2 | RADIOLABELED NANOHYBRIDS TARGETING SOLID TUMOR NEOVASCULATURE AND METHOD OF USING SAME | University of Maryland, Baltimore (US) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006012355-A2 | RADIOLABELED NANOHYBRIDS TARGETING SOLID TUMOR NEOVASCULATURE AND METHOD OF USING SAME | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2006-02-02 | — | — | WO | disclosed |