Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610844 | 0.83 | LMNA (0.50) | LMNAALDH1A1POLBTSHRHSD17B10 | |
| SCHEMBL5772766 | 0.83 | LMNA (0.50) | LMNAALDH1A1POLBTSHRHSD17B10 | |
| SCHEMBL2100563 | 0.81 | LMNA (0.51) | LMNAMAPTKDM4EALDH1A1POLB | |
| SCHEMBL734672 | 0.76 | TERT (0.46) | LMNAMAPTPOLBMMP2HSD17B10 | |
| SCHEMBL20955943 | 0.76 | TERT (0.46) | LMNAMAPTPOLBMMP2HSD17B10 | |
| SCHEMBL8528975 | 0.74 | L3MBTL1 (0.43) | ALDH1A1POLBHSD17B10METAP1 | |
| SCHEMBL8342292 | 0.73 | CCR2 (0.47) | MMP2MMP8METAP1 | |
| SCHEMBL6910643 | 0.73 | PTGS1 (0.51) | LMNAMAPTALDH1A1POLBPKM | |
| SCHEMBL7144696 | 0.70 | PTGS1 (0.43) | LMNAMAPTALDH1A1PKM | |
| SCHEMBL17941775 | 0.69 | FAAH (0.36) | LMNAALDH1A1HSD17B10MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080274941-A1 | DETERGENT OR CLEANSER DOSING UNIT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-11-06 | — | — | US | disclosed |