Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.44 |
| ▸ | PNP | P00491 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TK1 | P04183 | 2/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28695644 | 0.82 | XDH (0.43) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL523465 | 0.81 | XDH (0.47) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL986800 | 0.78 | XDH (0.60) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL15005119 | 0.77 | XDH (0.59) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL8057728 | 0.77 | ADORA2A (0.44) | — | |
| SCHEMBL28348671 | 0.74 | XDH (0.50) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL1831279 | 0.74 | XDH (0.50) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL3953063 | 0.74 | XDH (0.38) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL27631105 | 0.70 | XDH (0.49) | XDHPNPBLMUSP2TSHR | |
| SCHEMBL9241289 | 0.70 | XDH (0.50) | XDHPNPBLMUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9587238-B1 | Gene-targeted apoptosis | YALE UNIVERSITY (US) | 2017-03-07 | — | — | US | disclosed |
| US-20130203998-A1 | Synthesis of Drug Conjugates Via Reaction With Epoxide-Containing Linkers | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-08-08 | — | — | US | disclosed |
| US-8431714-B2 | Synthesis of drug conjugates via reaction with epoxide-containing linkers | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-04-30 | — | — | US | disclosed |
| US-20080312440-A1 | SYNTHESIS OF DRUG CONJUGATES VIA REACTION WITH EPOXIDE-CONTAINING LINKERS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-12-18 | — | — | US | disclosed |
| US-6143877-A | FORMING A TRIPLEX BY CONTACTING DUPLEX NUCLEIC ACID HAVING A TARGET SEQUENCE OF PURINE BASES WITH A OLIGONUCLEOTIDE HAVING AT LEAST ONE GUANINE BASE REPLACED BY 6-AMINO-1H-PYRAZOLO(3,4-D)PYRIMIDIN-4(5H)-ONE | EPOCH PHARMACEUTICALS, INC. (US) | 2000-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312440-A1 | SYNTHESIS OF DRUG CONJUGATES VIA REACTION WITH EPOXIDE-CONTAINING LINKERS | EPHX2, EPHX1, ENPP1 | XDH 2869/4885PNP 858/4885BLM 2931/4885 |
| US-20130203998-A1 | Synthesis of Drug Conjugates Via Reaction With Epoxide-Containing Linkers | EPHX2, EPHX1, ENPP1 | XDH 2869/4885PNP 858/4885BLM 2931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.