Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867774 | 0.87 | GRM6 (0.48) | ALDH1A1MAPTMEN1KMT2ASLC6A4 | |
| SCHEMBL2438024 | 0.87 | GRM6 (0.48) | ALDH1A1MAPTMEN1KMT2ASLC6A4 | |
| SCHEMBL4900649 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1MAPTCHRNB2CHRNA4 | |
| SCHEMBL21315843 | 0.81 | RORC (0.47) | RORCKDM4EALDH1A1MAPTCYP2D6 | |
| SCHEMBL21315844 | 0.81 | RORC (0.47) | RORCKDM4EALDH1A1MAPTCYP2D6 | |
| SCHEMBL2028510 | 0.78 | KDM4E (0.52) | RORCKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1820435 | 0.78 | KDM4E (0.52) | RORCKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL27712915 | 0.78 | SIGMAR1 (0.47) | ALDH1A1MAPTMEN1KMT2ASLC6A4 | |
| SCHEMBL4899837 | 0.77 | L3MBTL1 (0.51) | KDM4EALDH1A1MAPTSLC6A4 | |
| SCHEMBL1243297 | 0.77 | HPGD (0.41) | KDM4EALDH1A1MAPTCYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220175765-A1 | ROR-GAMMA MODULATORS | ESCALIER BIOSCIENCES B.V. | 2022-06-09 | — | — | US | disclosed |
| US-20080207630-A1 | 2-Aminocarbonyl Substituted Piperazine or Diaza-Cyclic Compounds as Apoptosis Protein Inhibitors (Iap) Modulators | ECKL ROBERT | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220175765-A1 | ROR-GAMMA MODULATORS | RORB, RORC, RORA | RORC 2/4885KDM4E 2636/4885ALDH1A1 167/4885 |
| US-20080207630-A1 | 2-Aminocarbonyl Substituted Piperazine or Diaza-Cyclic Compounds as Apoptosis Protein Inhibitors (Iap) Modulators | API5, BCL2, BIRC5 | RORC 3544/4885KDM4E 3213/4885ALDH1A1 3485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.