Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | IL2 | P60568 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2727890 | 0.88 | LMNA (0.49) | LMNAMAPTHTTKDM4EIL2 | |
| SCHEMBL16264949 | 0.87 | HTT (0.51) | LMNAMAPTHTTKDM4EIL2 | |
| SCHEMBL14743593 | 0.84 | HTT (0.49) | LMNAMAPTHTTKDM4EIL2 | |
| SCHEMBL14743510 | 0.81 | HTT (0.49) | LMNAMAPTHTTKDM4EIL2 | |
| SCHEMBL4910720 | 0.81 | HTT (0.46) | LMNAMAPTHTTKDM4EIL2 | |
| SCHEMBL9997018 | 0.81 | LMNA (0.46) | LMNAMAPTHTTKDM4EIL2 | |
| SCHEMBL4910062 | 0.80 | LMNA (0.48) | LMNAMAPTHTTKDM4EIL2 | |
| SCHEMBL471858 | 0.79 | KDM4E (0.60) | LMNAMAPTHTTKDM4EIL2 | |
| SCHEMBL1763999 | 0.78 | KDM4E (0.51) | LMNAMAPTHTTKDM4EIL2 | |
| SCHEMBL25342747 | 0.78 | LMNA (0.49) | LMNAMAPTHTTKDM4EIL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230287217-A1 | Zwitterionic Cell-Permeant and Water-Soluble Rhodamine Dyes for Quantitative Imaging Applications | OREGON HEALTH & SCIENCE UNIVERSITY | 2023-09-14 | — | — | US | disclosed |
| US-20230287217-A1 | Zwitterionic Cell-Permeant and Water-Soluble Rhodamine Dyes for Quantitative Imaging Applications | OREGON HEALTH & SCIENCE UNIVERSITY | 2023-09-14 | — | — | US | disclosed |
| US-20230287217-A1 | Zwitterionic Cell-Permeant and Water-Soluble Rhodamine Dyes for Quantitative Imaging Applications | OREGON HEALTH & SCIENCE UNIVERSITY | 2023-09-14 | — | — | US | disclosed |
| EP-4225122-A1 | ZWITTERIONIC CELL-PERMEANT AND WATER-SOLUBLE RHODAMINE DYES FOR QUANTITATIVE IMAGING APPLICATIONS | Oregon Health & Science University (US) | 2023-08-16 | — | — | EP | disclosed |
| US-9701841-B2 | Cell permeable, fluorescent dye | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2017-07-11 | — | — | US | disclosed |
| US-20160230011-A1 | CELL PERMEABLE, FLUORESCENT DYE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2016-08-11 | — | — | US | disclosed |
| US-20080076760-A1 | 2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION | WAKAMOTO PHARMACEUTICAL CO., LTD (JP) | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076760-A1 | 2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION | GABRA5, GABRA1, GABRB1 | LMNA 2104/4885MAPT 3584/4885HTT 4213/4885 |
| US-20160230011-A1 | CELL PERMEABLE, FLUORESCENT DYE | EPCAM, IK, TSPO | LMNA 1312/4885MAPT 4366/4885HTT 3033/4885 |
| US-20230287217-A1 | Zwitterionic Cell-Permeant and Water-Soluble Rhodamine Dyes for Quantitative Imaging Applications | SLC1A5, SLCO1B1, SLCO2B1 | LMNA 498/4885MAPT 2459/4885HTT 2492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.