SCHEMBL4901322

SCHEMBL4901322

CCCS(=O)(=O)ON=C(c1ccccc1C)C(Cl)(Cl)[N+](=O)[O-]

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
ALDH1A1 P00352 6/20 0.34
SMN1; SMN2 Q16637 4/20 0.34
HPGD P15428 3/20 0.34
POLB P06746 2/20 0.34
GAA P10253 2/20 0.32
MAPT P10636 5/20 0.32
KDM4E B2RXH2 2/20 0.32
HTT P42858 2/20 0.32
THRB P10828 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TBXA2R P21731 2/20 0.31
F2 P00734 1/20 0.31
PLAU P00749 1/20 0.31
ELANE P08246 1/20 0.31
VCAM1 P19320 1/20 0.31
HSD17B10 Q99714 1/20 0.31
FLT1 P17948 1/20 0.30
FLT4 P35916 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4897601 0.81 L3MBTL1 (0.35) NPC1RAB9AALDH1A1SMN1; SMN2MAPT
SCHEMBL4901942 0.81 L3MBTL1 (0.33) NPC1RAB9ASMN1; SMN2MAPTHTT
SCHEMBL5456788 0.78 L3MBTL1 (0.33) NPC1RAB9AALDH1A1SMN1; SMN2HPGD
SCHEMBL4897515 0.76 KMT2A (0.35) NPC1RAB9AALDH1A1SMN1; SMN2HPGD
SCHEMBL4900868 0.67 KMT2A (0.34) NPC1RAB9AALDH1A1SMN1; SMN2HPGD
SCHEMBL546605 0.66 CNR2 (0.39) HPGDKDM4EL3MBTL1
SCHEMBL546604 0.66 CNR2 (0.39) HPGDKDM4EL3MBTL1
SCHEMBL4905376 0.66 ALDH1A1 (0.39) NPC1RAB9AALDH1A1SMN1; SMN2HPGD
SCHEMBL4901776 0.64 NPSR1 (0.34) ALDH1A1SMN1; SMN2HPGDPOLBMAPT
SCHEMBL4903140 0.64 NPSR1 (0.34) ALDH1A1SMN1; SMN2HPGDPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US claimed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US claimed
US-20080187859-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2008-08-07 US disclosed
US-20070269735-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2007-11-22 US disclosed
US-7297461-B2 Radiation sensitive resin composition JSR CORPORATION (JP) 2007-11-20 US disclosed
EP-1736829-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-12-27 EP disclosed
EP-1726608-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-11-29 EP disclosed
US-20050171226-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2005-08-04 US disclosed
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US disclosed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US disclosed