SCHEMBL4897515

SCHEMBL4897515

CCCS(=O)(=O)ON=C(c1ccccc1C)C(F)(F)S(=O)(=O)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 4/20 0.32
TSHR P16473 2/20 0.32
ALDH1A1 P00352 2/20 0.32
GAA P10253 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KAT6A Q92794 1/20 0.32
ABCB1 P08183 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
HTT P42858 2/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
WDR5 P61964 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
NR1I2 O75469 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4900868 0.92 KMT2A (0.34) KMT2ASMN1; SMN2MAPTTSHRALDH1A1
SCHEMBL4895537 0.85 TDP1 (0.35) KMT2ATDP1MAPTALDH1A1GAA
SCHEMBL4894488 0.84 RAB9A (0.35) KMT2ASMN1; SMN2MAPTALDH1A1GAA
SCHEMBL4903237 0.80 HSD11B1 (0.43) KMT2ASMN1; SMN2TDP1MAPTALDH1A1
SCHEMBL6873824 0.79 PTGS2 (0.36) KMT2ATDP1MAPTKAT6AMEN1
SCHEMBL4901942 0.78 L3MBTL1 (0.33) KMT2ASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL6875352 0.78 PTGS2 (0.37) KMT2ATDP1MEN1
SCHEMBL4897601 0.78 L3MBTL1 (0.35) KMT2ASMN1; SMN2TDP1MAPTTSHR
SCHEMBL4902695 0.76 PSIP1 (0.35) KMT2AMAPTTSHRALDH1A1GAA
SCHEMBL4901322 0.76 NPC1 (0.36) KMT2ASMN1; SMN2MAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US claimed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US claimed
US-20080187859-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2008-08-07 US disclosed
US-20070269735-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2007-11-22 US disclosed
US-7297461-B2 Radiation sensitive resin composition JSR CORPORATION (JP) 2007-11-20 US disclosed
EP-1736829-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-12-27 EP disclosed
EP-1726608-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-11-29 EP disclosed
US-20050171226-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2005-08-04 US disclosed
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US disclosed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US disclosed