SCHEMBL4901685

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4894082	0.90	PGR (0.52)	PGRKDM4EMEN1MAPTKMT2A
	SCHEMBL3055801	0.88	PGR (0.54)	PGRKDM4EMEN1MAPTKMT2A
	SCHEMBL3060099	0.86	PGR (0.54)	PGRTRPV4ARCYP2C19KCNH2
	SCHEMBL3057297	0.85	PGR (0.44)	PGRKDM4EMEN1MAPTKMT2A
	SCHEMBL3054008	0.83	PGR (0.56)	PGRTRPV4ARCYP2C19KCNH2
	SCHEMBL3060094	0.81	PGR (0.54)	PGRTRPV4ARCYP2C19KCNH2
	SCHEMBL5346116	0.81	TRPV4 (0.46)	PGRTRPV4AR
	SCHEMBL4893922	0.80	PGR (0.53)	PGRS1PR1CYP2C19
	SCHEMBL11059504	0.80	S100B (0.55)	KDM4EMEN1MAPTKMT2AS1PR1
	SCHEMBL2677378	0.79	TRPV4 (0.52)	PGRTRPV4ARCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.