Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4902808 | 0.99 | L3MBTL1 (0.36) | L3MBTL1KMT2APOLBSLC7A5CYP4F2 | |
| Hydrochloric Acid SCHEMBL4902819 | 0.99 | L3MBTL1 (0.36) | L3MBTL1KMT2APOLBSLC7A5CYP4F2 | |
| SCHEMBL10210591 | 0.82 | NPSR1 (0.40) | KMT2APOLBCYP4F2CYP4A11CYP1A2 | |
| SCHEMBL4911646 | 0.77 | CTSK (0.43) | L3MBTL1CYP1A2TACR1 | |
| SCHEMBL16493531 | 0.77 | CTSK (0.43) | L3MBTL1CYP1A2TACR1 | |
| SCHEMBL4911639 | 0.77 | CTSK (0.43) | L3MBTL1CYP1A2TACR1 | |
| SCHEMBL28080073 | 0.73 | L3MBTL1 (0.45) | L3MBTL1KMT2APOLBCYP4F2CYP4A11 | |
| SCHEMBL13198572 | 0.71 | CYP4F2 (0.42) | L3MBTL1KMT2ACYP4F2CYP4A11KDM4E | |
| SCHEMBL29024345 | 0.69 | CYP4F2 (0.61) | CYP4F2CYP4A11NLRP3APPCYP1A2 | |
| SCHEMBL16387158 | 0.69 | CYP1A2 (0.47) | L3MBTL1KMT2APOLBCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1586564-B1 | 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICINAL USES THEREOF | ONO PHARMACEUTICAL CO (JP) | 2012-11-28 | — | — | EP | disclosed |
| EP-1586564-B1 | 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICINAL USES THEREOF | ONO PHARMACEUTICAL CO (JP) | 2012-11-28 | — | — | EP | disclosed |
| US-20080033033-A1 | 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. | 2008-02-07 | — | — | US | disclosed |
| US-20080033033-A1 | 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. | 2008-02-07 | — | — | US | disclosed |
| US-7256211-B1 | 8-azaprostaglandin derivatives and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-08-14 | — | — | US | disclosed |
| US-7256211-B1 | 8-azaprostaglandin derivatives and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-08-14 | — | — | US | disclosed |
| EP-1586564-A1 | 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICINAL USES THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033033-A1 | 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICAL USE THEREOF | HPGDS, PTGIS, PTGER4 | L3MBTL1 2879/4885KMT2A 4128/4885POLB 4291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.