Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10468127 | 0.81 | MAPT (0.37) | PKMMAPTKDM4EMEN1KMT2A | |
| SCHEMBL18048497 | 0.81 | PKM (0.37) | MAPK1PKMMAPTKDM4EMEN1 | |
| SCHEMBL18048519 | 0.79 | MAPK1 (0.36) | MAPK1PKMMAPTKDM4EKMT2A | |
| SCHEMBL4906424 | 0.76 | ALDH1A1 (0.35) | MAPT | |
| SCHEMBL22323568 | 0.73 | ALDH1A1 (0.37) | MAPK1PKMMAPTKDM4EMEN1 | |
| SCHEMBL7863109 | 0.73 | MEN1 (0.33) | PKMMAPTMEN1KMT2A | |
| SCHEMBL7859916 | 0.72 | MEN1 (0.57) | PKMMEN1KMT2A | |
| SCHEMBL2710202 | 0.72 | PKM (0.40) | MAPK1PKMMAPTKDM4EMEN1 | |
| SCHEMBL14818419 | 0.71 | TSHR (0.39) | — | |
| SCHEMBL283884 | 0.71 | MEN1 (0.46) | MAPK1PKMKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200679-A1 | Alpha-HYDROXY, alpha-SUBSTITUTED METHYLENEBISPHOSPHONATES AND PHOSPHONOACETATES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200679-A1 | Alpha-HYDROXY, alpha-SUBSTITUTED METHYLENEBISPHOSPHONATES AND PHOSPHONOACETATES | GRHPR, PHPT1, PHYKPL | MAPK1 2890/4885PKM 1040/4885MAPT 3518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.