SCHEMBL4903541

SCHEMBL4903541

CCS(=O)(=O)ON=C(c1ccccc1)C(F)(F)C#N

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.34
POLB P06746 2/20 0.34
SMN1; SMN2 Q16637 3/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 1/20 0.32
CTSL P07711 1/20 0.30
MAPT P10636 3/20 0.30
KMT2A Q03164 3/20 0.30
LMNA P02545 2/20 0.30
HTT P42858 2/20 0.30
MAPK1 P28482 1/20 0.30
ALDH1A1 P00352 2/20 0.30
CES1 P23141 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4903574 0.86 CES1 (0.32) NPSR1POLBSMN1; SMN2L3MBTL1NPC1
SCHEMBL4896478 0.81 PPARG (0.36) NPSR1POLBMAPTKMT2ALMNA
SCHEMBL4905378 0.80 CES1 (0.41) NPSR1POLBL3MBTL1MAPTLMNA
SCHEMBL4902695 0.80 PSIP1 (0.35) NPSR1POLBRAB9AMAPTKMT2A
SCHEMBL4892626 0.78 RECQL (0.36) SMN1; SMN2RAB9AMAPTKMT2ALMNA
SCHEMBL4895434 0.77 ALDH1A1 (0.35) NPSR1RAB9AMAPTKMT2ALMNA
SCHEMBL4902710 0.76 RAB9A (0.35) NPSR1POLBSMN1; SMN2RAB9AMAPT
SCHEMBL2700597 0.76 PLA2G7 (0.43) NPSR1POLBSMN1; SMN2L3MBTL1NPC1
SCHEMBL2700595 0.76 PLA2G7 (0.43) NPSR1POLBSMN1; SMN2L3MBTL1NPC1
SCHEMBL4896528 0.75 ELANE (0.39) NPSR1POLBSMN1; SMN2L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US claimed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US claimed
US-20080187859-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2008-08-07 US disclosed
US-20070269735-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2007-11-22 US disclosed
US-7297461-B2 Radiation sensitive resin composition JSR CORPORATION (JP) 2007-11-20 US disclosed
EP-1736829-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-12-27 EP disclosed
EP-1726608-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-11-29 EP disclosed
US-20050171226-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2005-08-04 US disclosed
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US disclosed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US disclosed