Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13864166 | 0.89 | MAPT (0.43) | MAPTKMT2AGAAMEN1USP2 | |
| SCHEMBL4449441 | 0.88 | MGLL (0.45) | MAPTKMT2AGAAHSD17B10MEN1 | |
| SCHEMBL5175560 | 0.87 | KDM4E (0.35) | MAPTKMT2AGAAHSD17B10MEN1 | |
| SCHEMBL4895048 | 0.87 | MAPT (0.32) | MAPTKMT2AGAAHSD17B10MEN1 | |
| SCHEMBL4903716 | 0.87 | CYP19A1 (0.33) | MAPTKMT2AGAAHSD17B10MEN1 | |
| SCHEMBL409034 | 0.83 | KDM4E (0.44) | MAPTKMT2AGAAMEN1USP2 | |
| SCHEMBL11136205 | 0.82 | MGLL (0.44) | MAPTKMT2AGAAHSD17B10MEN1 | |
| SCHEMBL411262 | 0.81 | F2 (0.40) | MAPTBLMALDH1A1CASP1 | |
| SCHEMBL5970022 | 0.80 | MGLL (0.47) | MAPTKMT2AGAAHSD17B10MEN1 | |
| SCHEMBL410345 | 0.80 | MGLL (0.47) | MAPTKMT2AGAAHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6753363-B1 | BASIC NITROGEN-CONTAINING COMPOUND, PHOSPHORUS COMPOUND FLAME RETARDANT, AND AROMATIC COMPOUND ACCELERATOR; MOLDABILITY | POLYPLASTICS CO., LTD. (JP) | 2004-06-22 | — | — | US | disclosed |