SCHEMBL7794809

SCHEMBL7794809

COc1cc(CCC(=O)O)cc(C(C)(C)C)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.54
RXRB P28702 2/20 0.54
RXRG P48443 2/20 0.54
FFAR1 O14842 5/20 0.47
POLB P06746 1/20 0.44
NR1H4 Q96RI1 2/20 0.43
EPHX2 P34913 1/20 0.43
ELANE P08246 1/20 0.41
CD69 Q07108 1/20 0.41
CYP24A1 Q07973 1/20 0.41
CALM1 P0DP23 1/20 0.41
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
PKM P14618 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10750814 0.88 LMNA (0.51) RXRARXRBRXRGNR1H4EPHX2
SCHEMBL14441580 0.86 RXRA (0.56) RXRARXRBRXRGFFAR1POLB
SCHEMBL490401 0.85 FFAR1 (0.56) FFAR1POLBLMNANFKB1NFKB2
SCHEMBL9702460 0.85 RXRA (0.70) RXRARXRBRXRGFFAR1NR1H4
SCHEMBL7794784 0.84 RXRA (0.52) RXRARXRBRXRGPOLBNR1H4
Methane SCHEMBL9419508 0.83 RXRA (0.68) RXRARXRBRXRGFFAR1NR1H4
SCHEMBL1792722 0.82 CALM1 (0.39) RXRARXRBRXRGNR1H4EPHX2
SCHEMBL7944737 0.80 ALOX5 (0.41) RXRARXRBRXRGCYP24A1CALM1
SCHEMBL1792723 0.80 CALM1 (0.40) NR1H4EPHX2CYP24A1CALM1MEN1
SCHEMBL23599377 0.79 FFAR1 (0.50) FFAR1POLBALDH1A1LMNATHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed