Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.64 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | IDE | P14735 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10277136 | 1.00 | TDP1 (0.64) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL13049575 | 1.00 | TDP1 (0.64) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL26490546 | 1.00 | TDP1 (0.64) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL7936987 | 1.00 | TDP1 (0.64) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL15482071 | 1.00 | TDP1 (0.64) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL4740816 | 0.99 | TDP1 (0.65) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL20711508 | 0.97 | TDP1 (0.62) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL20042594 | 0.97 | TDP1 (0.62) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL30735993 | 0.96 | TDP1 (0.61) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL31135784 | 0.96 | TDP1 (0.61) | TDP1PLCD1F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12578335-B2 | Bioprobes for lysyl oxidases and uses thereof | SYNTARA LIMITED (AU) | 2026-03-17 | — | — | US | disclosed |
| US-20230349907-A1 | BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2023-11-02 | — | — | US | disclosed |
| US-20230137943-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | THE UNIVERSITY OF CHICAGO | 2023-05-04 | — | — | US | disclosed |
| EP-4031550-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | The University of Chicago (US) | 2022-07-27 | — | — | EP | disclosed |
| CN-114728970-A | Optical proximity analysis of protein-protein interactions in cells | 芝加哥大学 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021055960-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | THE UNIVERSITY OF CHICAGO (US) | 2021-03-25 | — | — | WO | disclosed |
| US-20100252433-A1 | NOVEL OPTICAL LABELING MOLECULES FOR PROTEOMICS AND OTHER BIOLOGICAL ANALYSES | NATIONAL SCIENCE FOUNDATION | 2010-10-07 | — | — | US | disclosed |
| US-20080311609-A1 | Novel Molecular Probes | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | disclosed |
| US-20080311609-A1 | Novel Molecular Probes | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | disclosed |
| US-20080311609-A1 | Novel Molecular Probes | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | disclosed |
| EP-1831187-A1 | NOVEL MOLECULAR PROBES | AstraZeneca AB (SE) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006065218-A1 | NOVEL MOLECULAR PROBES | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100252433-A1 | NOVEL OPTICAL LABELING MOLECULES FOR PROTEOMICS AND OTHER BIOLOGICAL ANALYSES | PTMS, CHAMP1, RAB5IF | TDP1 2771/4885PLCD1 1626/4885F2 3692/4885 |
| US-20230349907-A1 | BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF | MAOB, LOX, LPO | TDP1 587/4885PLCD1 4380/4885F2 2220/4885 |
| US-20080311609-A1 | Novel Molecular Probes | BACE1, BACE2, PSEN1 | TDP1 270/4885PLCD1 1690/4885F2 4615/4885 |
| US-20230137943-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | PPIA, S100A4, S100A6 | TDP1 1641/4885PLCD1 2969/4885F2 1879/4885 |
| US-12578335-B2 | Bioprobes for lysyl oxidases and uses thereof | LOXL1, LOX, LOXL2 | TDP1 2300/4885PLCD1 3545/4885F2 948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.