Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | EED | O75530 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2485004 | 0.84 | HTR6 (1.00) | HTR6MAPTCYP2C19CYP2C9SMN1; SMN2 | |
| SCHEMBL2388121 | 0.83 | HTR6 (0.70) | HTR6MAPTCYP2C19CYP2C9SMN1; SMN2 | |
| SCHEMBL2482927 | 0.79 | HTR6 (1.00) | HTR6MAPTCYP2C19CYP2C9SMN1; SMN2 | |
| SCHEMBL2483606 | 0.76 | ALDH1A1 (0.69) | HTR6MAPTCYP2C19CYP2C9SMN1; SMN2 | |
| SCHEMBL1844148 | 0.74 | ALDH1A1 (0.81) | HTR6MAPTCYP2C19CYP2C9SMN1; SMN2 | |
| SCHEMBL6708642 | 0.74 | SIRT6 (0.56) | MAPTSMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL12205259 | 0.69 | MAPT (0.61) | HTR6MAPTCYP2C19CYP2C9SMN1; SMN2 | |
| SCHEMBL2484504 | 0.66 | MAPT (0.76) | HTR6MAPTCYP2C19CYP2C9SMN1; SMN2 | |
| SCHEMBL6712583 | 0.66 | MAPT (0.49) | MAPTCYP2C19CYP2C9SMN1; SMN2LMNA | |
| SCHEMBL31000456 | 0.65 | ALDH1A1 (1.00) | HTR6MAPTCYP2C19CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176854-A1 | Nitro-Substituted Phenyl-Piperazine Compounds, Their Preparation and Use in Medicaments | LABORATORIOS DEL DR. ESTEVE S.A (ES) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176854-A1 | Nitro-Substituted Phenyl-Piperazine Compounds, Their Preparation and Use in Medicaments | HTR6, HTR5A, P2RX5 | HTR6 1/4885MAPT 3000/4885CYP2C19 287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.