SCHEMBL490622

SCHEMBL490622

C=CC(=O)n1c(=O)ccn(C)c1=O

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.32
KDM4E B2RXH2 1/20 0.32
KDM6A O15550 1/20 0.32
KDM4A O75164 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
KDM5C P41229 1/20 0.32
KDM2B Q8NHM5 1/20 0.32
DOHH Q9BU89 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
GSK3B P49841 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6937494 0.70 LMNA (0.46) CYP2C9CYP2C19CYP2D6
SCHEMBL7154082 0.69 LMNA (0.35) ACHECYP2D6TSHRGSK3B
SCHEMBL100263 0.65 CRBN (0.44) KDM4EKDM6AKDM4ACYP2C9CYP2C19
SCHEMBL17226145 0.63 CYP2D6 (0.31) ACHECYP2D6TSHR
Trimethylammonium SCHEMBL9619224 0.63 ACHE (0.36) ACHEKDM2BKDM2ACYP2D6TSHR
SCHEMBL23222667 0.62 CRBN (0.37) KDM4EKDM6AKDM4ACYP2C9CYP2C19
SCHEMBL2078819 0.62 CRBN (0.37) KDM4EKDM6AKDM4ACYP2C9CYP2C19
SCHEMBL19577292 0.62 CRBN (0.37) KDM4EKDM6AKDM4ACYP2C9CYP2C19
SCHEMBL5478056 0.62 KDM4E (0.35) KDM4EKDM6AKDM4ACYP2C9CYP2C19
SCHEMBL7607451 0.61 ADORA2B (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230055665-A1 DELIVERY CARRIER INTO CELL ITO, KABUSIKIKAISYA (JP) 2023-02-23 US claimed
US-8486722-B1 Sensing method for biopolymers and sensing device therefor NATIONAL UNIVERSITY CORPORATION TOYOHASHI UNIVERSITY OF TECHNOLOGY (JP) 2013-07-16 US claimed
US-20130164862-A1 SENSING METHOD FOR BIOPOLYMERS AND SENSING DEVICE THEREFOR TANAKA SABURO (JP) 2013-06-27 US claimed
US-20070218567-A1 SENSING METHOD FOR BIOPOLYMERS AND SENSING DEVICE THEREFOR NATIONAL UNIV CORP TOYOHASHI UNIV OF TECHNOLOGY (JP) 2007-09-20 US claimed
CN-115135307-B Cell delivery vehicle 株式会社ITO 2024-11-22 CN disclosed
US-20230273455-A1 OPTICALLY ACTIVE DEVICES JOHNSON & JOHNSON SURGICAL VISION INC (US) 2023-08-31 US disclosed
EP-4182736-A1 OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2023-05-24 EP disclosed
US-20230055665-A1 DELIVERY CARRIER INTO CELL ITO, KABUSIKIKAISYA (JP) 2023-02-23 US disclosed
CN-115135307-A Carrier for cell delivery 株式会社ITO 2022-09-30 CN disclosed
WO-2022012798-A1 OPTICALLY ACTIVE DEVICES MERCK PATENT GMBH (DE) 2022-01-20 WO disclosed
US-20190170758-A1 METHOD OF DETECTION WITH A FLUORESCENT LABELING PARTICLE FURUKAWA ELECTRIC CO., LTD. (JP) 2019-06-06 US disclosed
US-10203326-B2 Method of detecting target substance FURUKAWA ELECTRIC CO., LTD. (JP) 2019-02-12 US disclosed
US-20110233453-A1 METHOD OF STORING THERMORESPONSIVE POLYMER IN STATE OF AQUEOUS SOLUTION CHISSO CORPORATION (JP) 2011-09-29 US disclosed
US-7976728-B2 Aqueous solution of polymer having upper critical solution temperature, aqueous dispersion of particle modified with the polymer and method of storing the same JNC CORPORATION (JP) 2011-07-12 US disclosed
EP-2009044-B1 Method of storing an aqueous dispersion of particle modified with a polymer having upper critical solution temperature JNC CORP (JP) 2011-06-15 EP disclosed
US-20090001321-A1 AQUEOUS SOLUTION OF POLYMER HAVING UPPER CRITICAL SOLUTION TEMPERATURE, AQUEOUS DISPERSION OF PARTICLE MODIFIED WITH THE POLYMER AND METHOD OF STORING THE SAME CHISSO CORPORATION (JP) 2009-01-01 US disclosed
US-20090001025-A1 AGGREGATION AND DISPERSION METHODS OF MAGNETIC PARTICLES, SEPARATION AND DETECTION METHODS USING THE SAME AND DETECTION KIT CHISSO CORPORATION (JP) 2009-01-01 US disclosed
EP-2009044-A1 Aqueous solution of polymer having upper critical solution temperature, aqueous dispersion of particle modified with the polymer and method of storing the same Chisso Corporation (JP) 2008-12-31 EP disclosed
EP-2009442-A2 Aggregation and dispersion methods of magnetic particles, separation and detection methods using the same and detection kit Chisso Corporation (JP) 2008-12-31 EP disclosed
US-20070218567-A1 SENSING METHOD FOR BIOPOLYMERS AND SENSING DEVICE THEREFOR NATIONAL UNIV CORP TOYOHASHI UNIV OF TECHNOLOGY (JP) 2007-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230055665-A1 DELIVERY CARRIER INTO CELL CTSA, ATG4A, ATG7 ACHE 3074/4885KDM4E 3872/4885KDM6A 2362/4885
US-20230273455-A1 OPTICALLY ACTIVE DEVICES PDE6C, PDE6A, PDE6D ACHE 635/4885KDM4E 3587/4885KDM6A 1553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.