Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | LPO | P22079 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4284400 | 0.82 | LPO (0.41) | L3MBTL1LPOMEN1KMT2ACYP2C9 | |
| SCHEMBL11800949 | 0.72 | L3MBTL1 (0.46) | LMNAL3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL10268206 | 0.69 | MEN1 (0.66) | LMNAL3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL16130857 | 0.69 | P2RX4 (0.45) | LMNAL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL10990597 | 0.69 | HPGD (0.48) | LMNAL3MBTL1CYP1A2LPOMEN1 | |
| SCHEMBL6219930 | 0.68 | CA12 (0.51) | LMNACYP1A2CYP3A4NPSR1BAZ2B | |
| SCHEMBL5722231 | 0.67 | ADORA3 (0.48) | LMNAL3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL7548711 | 0.67 | NUDT1 (0.38) | LMNAL3MBTL1CYP1A2LPOMEN1 | |
| SCHEMBL21911678 | 0.66 | ALDH1A1 (0.39) | L3MBTL1CYP1A2GAACYP3A4ALDH1A1 | |
| SCHEMBL10768056 | 0.65 | KDM4E (0.40) | LMNAL3MBTL1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1290169-A2 | CYSTINE-KNOT POLYPEPTIDES: CLOAKED-2 MOLECULES AND USES THEREOF | Amgen, Inc. (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001092308-A2 | CYSTINE-KNOT POLYPEPTIDES: CLOAKED-2 MOLECULES AND USES THEREOF | AMGEN, INC. (US) | 2001-12-06 | — | — | WO | disclosed |