SCHEMBL4906544

SCHEMBL4906544

N#C/C(=C/c1ccc(Cl)cc1)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.64
ALDH1A1 P00352 5/20 0.64
RAB9A P51151 4/20 0.64
MAPK1 P28482 2/20 0.64
L3MBTL1 Q9Y468 2/20 0.64
ESR1 P03372 2/20 0.58
ESR2 Q92731 2/20 0.58
NPSR1 Q6W5P4 2/20 0.57
GLA P06280 1/20 0.57
NPC1 O15118 3/20 0.56
KIF20A O95235 1/20 0.56
LMNA P02545 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
KDM4E B2RXH2 3/20 0.55
HTT P42858 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
HPGD P15428 2/20 0.54
THRB P10828 1/20 0.54
CYP1A2 P05177 2/20 0.51
CYP2D6 P10635 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4906546 1.00 MAPT (0.64) MAPTALDH1A1RAB9AMAPK1L3MBTL1
SCHEMBL4912768 1.00 MAPT (0.64) MAPTALDH1A1RAB9AMAPK1L3MBTL1
SCHEMBL27983745 0.93 ESR1 (0.58) MAPTALDH1A1RAB9AMAPK1L3MBTL1
SCHEMBL13485321 0.91 ESR1 (0.69) MAPTALDH1A1RAB9AMAPK1L3MBTL1
SCHEMBL11822854 0.91 ALDH1A1 (0.74) MAPTALDH1A1RAB9AMAPK1L3MBTL1
SCHEMBL11822838 0.91 ALDH1A1 (0.74) MAPTALDH1A1RAB9AMAPK1L3MBTL1
SCHEMBL247444 0.87 RAB9A (0.69) MAPTALDH1A1RAB9AMAPK1L3MBTL1
SCHEMBL347800 0.87 RAB9A (0.69) MAPTALDH1A1RAB9AMAPK1L3MBTL1
SCHEMBL247445 0.87 RAB9A (0.69) MAPTALDH1A1RAB9AMAPK1L3MBTL1
SCHEMBL4562175 0.85 MAPT (0.67) MAPTALDH1A1RAB9AMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1791901-B1 STABILIZATION OF ORGANIC MATERIALS BASF SE (DE) 2018-03-28 EP disclosed
US-9051448-B2 Stabilization of organic materials BASF SE (DE) 2015-06-09 US disclosed
US-20080269382-A1 Stabilization of Organic Materials BASF SE (DE) 2008-10-30 US disclosed
EP-1791901-A2 STABILIZATION OF ORGANIC MATERIALS Ciba SC Holding AG (CH) 2007-06-06 EP disclosed
WO-2006024611-A2 STABILIZATION OF ORGANIC MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269382-A1 Stabilization of Organic Materials LPO, PPOX, HMOX1 MAPT 128/4885ALDH1A1 129/4885RAB9A 4024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.