Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MITF | O75030 | 2/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791429 | 0.70 | KDM4E (0.47) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL11218549 | 0.70 | RAB9A (0.42) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL28078244 | 0.68 | — | — | |
| SCHEMBL12264964 | 0.68 | MEN1 (0.55) | SMN1; SMN2ENPP3ENPP1KMT2AMEN1 | |
| SCHEMBL3421833 | 0.68 | KMT2A (0.59) | SMN1; SMN2ENPP3ENPP1KMT2AMEN1 | |
| SCHEMBL8989162 | 0.67 | SMN1; SMN2 (0.56) | SMN1; SMN2ENPP3ENPP1KMT2AMEN1 | |
| SCHEMBL23921025 | 0.66 | KMT2A (0.56) | SMN1; SMN2ENPP3ENPP1KMT2AMEN1 | |
| SCHEMBL4910639 | 0.66 | CYP11B1 (0.59) | SMN1; SMN2ENPP3ENPP1KMT2AMEN1 | |
| SCHEMBL4401760 | 0.66 | KMT2A (0.56) | SMN1; SMN2ENPP3ENPP1KMT2AMEN1 | |
| SCHEMBL13173500 | 0.66 | KMT2A (0.63) | SMN1; SMN2ENPP3ENPP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132698-A1 | Use of N-oxide compounds in coupling reactions | UNIVERSITY OF OTTAWA | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132698-A1 | Use of N-oxide compounds in coupling reactions | CYP4X1, CYP4F3, CYP1A2 | SMN1; SMN2 2279/4885ENPP3 1208/4885ENPP1 1903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.