SCHEMBL4907222

SCHEMBL4907222

O=C(O)CCSc1ccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)c(Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.42
TP53 P04637 1/20 0.42
PRKAG1 P54619 1/20 0.38
PRKAA2 P54646 1/20 0.38
PRKAB1 Q9Y478 1/20 0.38
PPARD Q03181 2/20 0.35
PPARA Q07869 2/20 0.35
NPSR1 Q6W5P4 4/20 0.34
HTT P42858 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
PRNP P04156 3/20 0.33
RXFP1 Q9HBX9 3/20 0.33
MAPK10 P53779 2/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GAA P10253 1/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.32
POLB P06746 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL353399 0.81 ALDH1A1 (0.40) SMN1; SMN2PRKAG1PRKAA2PRKAB1NPSR1
SCHEMBL29366387 0.76 PRKAG1 (0.38) SMN1; SMN2TP53PRKAG1PRKAA2PRKAB1
SCHEMBL1355381 0.76 PRKAG1 (0.38) SMN1; SMN2TP53PRKAG1PRKAA2PRKAB1
SCHEMBL17145191 0.74 RXFP1 (0.42) SMN1; SMN2PRKAG1PRKAA2PRKAB1NPSR1
SCHEMBL11068279 0.74 HTT (0.53) SMN1; SMN2TP53PRKAG1PRKAA2PRKAB1
SCHEMBL29281059 0.73 ALDH1A1 (0.51) SMN1; SMN2KDM4EMEN1KMT2AALDH1A1
SCHEMBL13648646 0.72 ALDH1A1 (0.35) SMN1; SMN2PRKAG1PRKAA2PRKAB1NPSR1
SCHEMBL30888553 0.70 FABP4 (0.43) SMN1; SMN2TP53PRKAG1PRKAA2PRKAB1
SCHEMBL17145189 0.69 HPGD (0.36) SMN1; SMN2HTTGAAALDH1A1HPGD
SCHEMBL1356152 0.69 PKM (0.40) SMN1; SMN2TP53NPSR1HTTPRNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9152041-B2 Display panel including patterned spacer LG CHEM, LTD. (KR) 2015-10-06 US disclosed
EP-1779197-B1 DISPLAY PANEL INCLUDIDNG PATTERNED SPACER LG CHEMICAL LTD (KR) 2013-11-20 EP disclosed
US-20080213514-A1 Obtained from a photosensitive resin composition comprising a 2,4-bis(trichloromethyl)-6-(p-substituted alkylthiophenyl) triazine photoiniator, an alkali-soluble photocurable binder, and a monomer such as dipentaerythritol hexaacrylate; high strength, sensitivity, residue characteristics, film uniformity LG CHEM, LTD. (KR) 2008-09-04 US disclosed