SCHEMBL490759

SCHEMBL490759

Clc1ccc(C2=NC(c3ccccc3Cl)(C3(c4ccccc4Cl)N=C(c4ccc(Cl)cc4Cl)C(c4ccc(Cl)cc4Cl)=N3)N=C2c2ccc(Cl)cc2Cl)c(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.40
NPC1 O15118 3/20 0.40
ALDH1A1 P00352 3/20 0.40
RAB9A P51151 3/20 0.40
HPGD P15428 2/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HSD17B10 Q99714 1/20 0.40
HSD11B1 P28845 3/20 0.38
AHR P35869 1/20 0.38
PDK2 Q15119 1/20 0.37
CRHR1 P34998 3/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRG2 P18507 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL491055 0.88 AHR (0.41) SMN1; SMN2NPC1ALDH1A1RAB9AHPGD
SCHEMBL491173 0.86 NPC1 (0.37) SMN1; SMN2NPC1ALDH1A1RAB9AHPGD
SCHEMBL1425804 0.84 CYP2A6 (0.40) SMN1; SMN2NPC1ALDH1A1RAB9AHPGD
SCHEMBL18037939 0.78 CYP1A2 (0.45) SMN1; SMN2NPC1ALDH1A1RAB9ATSHR
SCHEMBL491288 0.77 CYP1A2 (0.40) SMN1; SMN2NPC1ALDH1A1RAB9ATP53
SCHEMBL490732 0.76 GABRA1 (0.36) SMN1; SMN2PDK2KMT2AGABRA1GABRA5
SCHEMBL80380 0.75 CHRM1 (0.41) SMN1; SMN2NPC1ALDH1A1RAB9AHPGD
SCHEMBL3389825 0.70 MEN1 (0.52) SMN1; SMN2NPC1ALDH1A1RAB9AHPGD
SCHEMBL29416163 0.69 AHR (0.52) SMN1; SMN2NPC1ALDH1A1RAB9AHPGD
SCHEMBL2934558 0.69 AHR (0.52) SMN1; SMN2NPC1ALDH1A1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8741536-B2 Light sensitive coating compositions useful for lithographic elements IBF Industria Basileira de Filmes S/A (BR) 2014-06-03 US claimed
EP-1673663-B1 LIGHT SENSITIVE COATING COMPOSITIONS FOR LITHOGRAPHIC ELEMENTS IBF IND BRASILEIRA DE FILMES SA (BR) 2011-03-23 EP claimed
US-20070202434-A1 Light Sensitive Coating Compositions Useful For Lithographic Elements IBF INDUSTRIA BRASILEIRA DE FILMES S/A (BR) 2007-08-30 US claimed
US-10254646-B2 Composition sensitive to radiation in electromagnetic spectrum ranges for printing purposes, printing plate comprising said composition, use of said composition and image development process IBF INDUSTRIA BRASILEIRA DE FILMES S/A (BR) 2019-04-09 US disclosed
US-9341743-B2 Photosensitive resin composition for color filter, and color filter prepared using the same CHEIL INDUSTRIES INC. (KR) 2016-05-17 US disclosed
US-9297940-B2 Photosensitive resin composition and color filter prepared using the same CHEIL INDUSTRIES INC. (KR) 2016-03-29 US disclosed
US-20160026080-A1 COMPOSITION SENSITIVE TO RADIATION IN ELECTROMAGNETIC SPECTRUM RANGES FOR PRINTING PURPOSES, PRINTING PLATE COMPRISING SAID COMPOSITION, USE OF SAID COMPOSITION AND IMAGE DEVLOPMENT PROCESS IBF INDUSTRIA BRASILEIRA DE FILMES S/A (BR) 2016-01-28 US disclosed
US-9146465-B2 Photosensitive resin composition and color filter using the same CHEIL INDUSTRIES INC. (KR) 2015-09-29 US disclosed
US-20150053900-A1 Photosensitive Resin Composition for Color Filter, and Color Filter Prepared Using the Same CHEIL INDUSTRIES INC. (KR) 2015-02-26 US disclosed
US-20150028271-A1 Photosensitive Resin Composition and Color Filter Prepared Using the Same CHEIL INDUSTRIES INC. (KR) 2015-01-29 US disclosed
US-8920689-B2 Photosensitive resin composition for color filter and color filter using the same CHEIL INDUSTRIES INC. (KR) 2014-12-30 US disclosed
US-5723260-A LIGHT SENSITIVE ELEMENTS AND STORAGE STABILITY MITSUBISHI CHEMICAL CORPORATION (JP) 1998-03-03 US disclosed
US-5686231-A Process for disposing of developer for pigment-containing non-silver-salt photo sensitive material, apparatus therefor and automatic developing system MITSUBISHI CHEMICAL CORPORATION (JP) 1997-11-11 US disclosed
EP-0793145-A1 Photopolymerizable composition for a photosensitive lithographic printing plate and photosensitive lithographic printing plate employing it MITSUBISHI CHEMICAL CORPORATION (JP) 1997-09-03 EP disclosed
EP-0780731-A2 Photopolymerizable composition for a color filter, color filter and liquid crystal display device MITSUBISHI CHEMICAL CORPORATION (JP) 1997-06-25 EP disclosed
EP-0763779-A2 Unsaturated group-containing urethane compound, photopolymerizable composition containing it, and photosensitive lithographic printing plate Mitsubishi Chemical Corporation (JP) 1997-03-19 EP disclosed
EP-0756204-A1 Photopolymerizable composition and photosensitive lithographic printing plate employing it MITSUBISHI CHEMICAL CORPORATION (JP) 1997-01-29 EP disclosed
EP-0747773-A1 METHOD AND APPARATUS FOR TREATING DEVELOPER FOR PIGMENT-CONTAINING NONSILVER PHOTOSENSITIVE MATERIAL, AND AUTOMATIC DEVELOPING MACHINE MITSUBISHI CHEMICAL CORPORATION (JP) 1996-12-11 EP disclosed
EP-0738929-A2 Photopolymerizable sensitive material Mitsubishi Chemical Corporation (JP) 1996-10-23 EP disclosed
EP-0723167-A2 Photopolymerizable composition for a color filter Mitsubishi Chemical Corporation (JP) 1996-07-24 EP disclosed