SCHEMBL490732

SCHEMBL490732

Clc1ccccc1C1(C2(c3ccccc3Cl)N=C(c3ccc(Br)cc3Br)C(c3ccc(Br)cc3Br)=N2)N=C(c2ccc(Br)cc2Br)C(c2ccc(Br)cc2Br)=N1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
GABRA2 P47869 1/20 0.36
GABRB2 P47870 1/20 0.36
PDK2 Q15119 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MAPT P10636 2/20 0.35
PIM1 P11309 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
PIM3 Q86V86 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
NQO2 P16083 1/20 0.33
GPR35 Q9HC97 1/20 0.32
PTGES O14684 6/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5150338 0.78 ALDH1A1 (0.38) GABRA1GABRA5GABRA3GABRA2GABRB2
SCHEMBL1425804 0.77 CYP2A6 (0.40) GABRA1GABRA5GABRA3GABRA2GABRB2
SCHEMBL490759 0.76 SMN1; SMN2 (0.40) GABRA1GABRA5GABRA3GABRA2GABRB2
SCHEMBL18037939 0.74 CYP1A2 (0.45) SMN1; SMN2MAPTPTGESKMT2ATAAR1
SCHEMBL491173 0.73 NPC1 (0.37) PDK2SMN1; SMN2MAPTKMT2A
SCHEMBL6298557 0.69 HSP90AA1 (0.40) PDK2SMN1; SMN2MAPTNQO2KMT2A
SCHEMBL2496616 0.68 CHRM1 (0.38) GABRA1GABRA5GABRA3GABRA2GABRB2
SCHEMBL491288 0.67 CYP1A2 (0.40) PDK2SMN1; SMN2MAPTGAATAAR1
SCHEMBL5555835 0.66 PDK2 (0.41) PDK2SMN1; SMN2MAPTCYP3A4KMT2A
SCHEMBL491344 0.65 TAAR1 (0.36) PDK2SMN1; SMN2GAAKMT2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160026080-A1 COMPOSITION SENSITIVE TO RADIATION IN ELECTROMAGNETIC SPECTRUM RANGES FOR PRINTING PURPOSES, PRINTING PLATE COMPRISING SAID COMPOSITION, USE OF SAID COMPOSITION AND IMAGE DEVLOPMENT PROCESS IBF INDUSTRIA BRASILEIRA DE FILMES S/A (BR) 2016-01-28 US claimed
US-8741536-B2 Light sensitive coating compositions useful for lithographic elements IBF Industria Basileira de Filmes S/A (BR) 2014-06-03 US claimed
EP-1673663-B1 LIGHT SENSITIVE COATING COMPOSITIONS FOR LITHOGRAPHIC ELEMENTS IBF IND BRASILEIRA DE FILMES SA (BR) 2011-03-23 EP claimed
US-20070202434-A1 Light Sensitive Coating Compositions Useful For Lithographic Elements IBF INDUSTRIA BRASILEIRA DE FILMES S/A (BR) 2007-08-30 US claimed
EP-1673663-A1 LIGHT SENSITIVE COATING COMPOSITIONS USEFUL FOR LITHOGRAPHIC ELEMENTS IBF Industria Brasileira de Filmes Ltda. (BR) 2006-06-28 EP claimed
WO-2005029186-A1 LIGHT SENSITIVE COATING COMPOSITIONS USEFUL FOR LITHOGRAPHIC ELEMENTS IBF Indústria Brasileira de Filmes Ltda. (BR) 2005-03-31 WO claimed
US-10254646-B2 Composition sensitive to radiation in electromagnetic spectrum ranges for printing purposes, printing plate comprising said composition, use of said composition and image development process IBF INDUSTRIA BRASILEIRA DE FILMES S/A (BR) 2019-04-09 US disclosed
US-20160026080-A1 COMPOSITION SENSITIVE TO RADIATION IN ELECTROMAGNETIC SPECTRUM RANGES FOR PRINTING PURPOSES, PRINTING PLATE COMPRISING SAID COMPOSITION, USE OF SAID COMPOSITION AND IMAGE DEVLOPMENT PROCESS IBF INDUSTRIA BRASILEIRA DE FILMES S/A (BR) 2016-01-28 US disclosed
US-8741536-B2 Light sensitive coating compositions useful for lithographic elements IBF Industria Basileira de Filmes S/A (BR) 2014-06-03 US disclosed
US-8652759-B2 Processing of lithographic printing plates with a developer solution containing a hydrophilic polymer EASTMAN KODAK COMPANY (US) 2014-02-18 US disclosed
US-8632937-B2 UV-sensitive lithographic printing plate precursor with benzoxazole derivative and analogues thereof as sensitizer EASTMAN KODAK COMPANY (US) 2014-01-21 US disclosed
EP-1849600-B1 Bakeable radiation-sensitive elements with a high resistance to chemicals EASTMAN KODAK CO (US) 2013-12-11 EP disclosed
US-8507181-B2 Method for developing and sealing of lithographic printing plates KODAK (NEAR EAST) INC. 2013-08-13 US disclosed
US-5723260-A LIGHT SENSITIVE ELEMENTS AND STORAGE STABILITY MITSUBISHI CHEMICAL CORPORATION (JP) 1998-03-03 US disclosed
US-5686231-A Process for disposing of developer for pigment-containing non-silver-salt photo sensitive material, apparatus therefor and automatic developing system MITSUBISHI CHEMICAL CORPORATION (JP) 1997-11-11 US disclosed
EP-0793145-A1 Photopolymerizable composition for a photosensitive lithographic printing plate and photosensitive lithographic printing plate employing it MITSUBISHI CHEMICAL CORPORATION (JP) 1997-09-03 EP disclosed
EP-0763779-A2 Unsaturated group-containing urethane compound, photopolymerizable composition containing it, and photosensitive lithographic printing plate Mitsubishi Chemical Corporation (JP) 1997-03-19 EP disclosed
EP-0756204-A1 Photopolymerizable composition and photosensitive lithographic printing plate employing it MITSUBISHI CHEMICAL CORPORATION (JP) 1997-01-29 EP disclosed
EP-0747773-A1 METHOD AND APPARATUS FOR TREATING DEVELOPER FOR PIGMENT-CONTAINING NONSILVER PHOTOSENSITIVE MATERIAL, AND AUTOMATIC DEVELOPING MACHINE MITSUBISHI CHEMICAL CORPORATION (JP) 1996-12-11 EP disclosed
EP-0738929-A2 Photopolymerizable sensitive material Mitsubishi Chemical Corporation (JP) 1996-10-23 EP disclosed