SCHEMBL491055

SCHEMBL491055

Clc1ccc(C2=NC(c3ccc(Cl)cc3Cl)(C3(c4ccc(Cl)cc4Cl)N=C(c4ccc(Cl)cc4Cl)C(c4ccc(Cl)cc4Cl)=N3)N=C2c2ccc(Cl)cc2Cl)c(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.41
HSD11B1 P28845 2/20 0.41
RAB9A P51151 3/20 0.38
HSP90AA1 P07900 2/20 0.38
HSP90AB1 P08238 2/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
TP53 P04637 2/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
CRHR1 P34998 4/20 0.36
NPC1 O15118 2/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL490759 0.88 SMN1; SMN2 (0.40) AHRHSD11B1RAB9AALDH1A1KDM4E
SCHEMBL491173 0.80 NPC1 (0.37) AHRHSD11B1RAB9AALDH1A1KDM4E
SCHEMBL80380 0.79 CHRM1 (0.41) HSD11B1RAB9AALDH1A1TP53SLC6A3
SCHEMBL11278246 0.76 ALDH1A1 (0.45) RAB9AALDH1A1TP53NPC1LMNA
SCHEMBL31379950 0.72 TP53 (0.42) HSD11B1ALDH1A1TP53SLC6A4SLC6A3
SCHEMBL29624840 0.70 AHR (0.64) AHRHSD11B1RAB9AHSP90AA1HSP90AB1
SCHEMBL464507 0.70 AHR (0.64) AHRHSD11B1RAB9AHSP90AA1HSP90AB1
SCHEMBL308751 0.69 HSD11B1 (0.38) HSD11B1KDM4EGAACRHR1LMNA
SCHEMBL11852382 0.67 TP53 (0.41) HSD11B1ALDH1A1TP53SLC6A4SLC6A3
SCHEMBL18037939 0.64 CYP1A2 (0.45) RAB9AHSP90AA1ALDH1A1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8652759-B2 Processing of lithographic printing plates with a developer solution containing a hydrophilic polymer EASTMAN KODAK COMPANY (US) 2014-02-18 US disclosed
US-8632937-B2 UV-sensitive lithographic printing plate precursor with benzoxazole derivative and analogues thereof as sensitizer EASTMAN KODAK COMPANY (US) 2014-01-21 US disclosed
EP-1849600-B1 Bakeable radiation-sensitive elements with a high resistance to chemicals EASTMAN KODAK CO (US) 2013-12-11 EP disclosed
US-8507181-B2 Method for developing and sealing of lithographic printing plates KODAK (NEAR EAST) INC. 2013-08-13 US disclosed
US-8361701-B2 Method for making lithographic plates EASTMAN KODAK COMPANY (US) 2013-01-29 US disclosed
EP-2293144-B1 Method of drying lithographic printing plates after single-step-processing EASTMAN KODAK CO (US) 2012-11-07 EP disclosed
US-20120152139-A1 METHOD AND APPARATUS FOR DRYING AFTER SINGLE-STEP-PROCESSING OF LITHOGRAPHIC PRINTING PLATES QUALEX INC. 2012-06-21 US disclosed
US-8137891-B2 Bakeable lithographic printing plates with a high resistance to chemicals EASTMAN KODAK COMPANY (US) 2012-03-20 US disclosed
US-8119331-B2 Photopolymer composition usable for lithographic plates KODAK GRAPHIC COMMUNICATIONS GMBH (DE) 2012-02-21 US disclosed
US-8105755-B2 Method for processing of photopolymer printing plates with overcoat EASTMAN KODAK COMPANY (US) 2012-01-31 US disclosed
EP-0756204-B1 Photopolymerizable composition and photosensitive lithographic printing plate employing it MITSUBISHI CHEM CORP (JP) 2000-09-20 EP disclosed
US-5837422-A ON A SUSTRATE CONTATINING ADDITION POLYMERIZABLE UNSATURATED BONDS WITH AND WITHOUT URETHANE BONDS; HIGH SENSITIVITY TO LIGNT IN VISIBLE REGION AND EXCELLENT DEVELOPABILITY MITSUBISHI CHEMICAL CORPORATION (JP) 1998-11-17 US disclosed
US-5800965-A LIGHT SENSITIVE LITHOGRAPHIC PLATES AND ADDITION POLYMERIZABLE MONOMERS AND PHOSPHORIC ACID DERIVATIVES MITSUBISHI CHEMICAL CORPORATION (JP) 1998-09-01 US disclosed
US-5723260-A LIGHT SENSITIVE ELEMENTS AND STORAGE STABILITY MITSUBISHI CHEMICAL CORPORATION (JP) 1998-03-03 US disclosed
US-5686231-A Process for disposing of developer for pigment-containing non-silver-salt photo sensitive material, apparatus therefor and automatic developing system MITSUBISHI CHEMICAL CORPORATION (JP) 1997-11-11 US disclosed
EP-0793145-A1 Photopolymerizable composition for a photosensitive lithographic printing plate and photosensitive lithographic printing plate employing it MITSUBISHI CHEMICAL CORPORATION (JP) 1997-09-03 EP disclosed
EP-0763779-A2 Unsaturated group-containing urethane compound, photopolymerizable composition containing it, and photosensitive lithographic printing plate Mitsubishi Chemical Corporation (JP) 1997-03-19 EP disclosed
EP-0756204-A1 Photopolymerizable composition and photosensitive lithographic printing plate employing it MITSUBISHI CHEMICAL CORPORATION (JP) 1997-01-29 EP disclosed
EP-0747773-A1 METHOD AND APPARATUS FOR TREATING DEVELOPER FOR PIGMENT-CONTAINING NONSILVER PHOTOSENSITIVE MATERIAL, AND AUTOMATIC DEVELOPING MACHINE MITSUBISHI CHEMICAL CORPORATION (JP) 1996-12-11 EP disclosed
EP-0738929-A2 Photopolymerizable sensitive material Mitsubishi Chemical Corporation (JP) 1996-10-23 EP disclosed