Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6393160 | 0.92 | LMNA (0.50) | NPC1RAB9ALMNAHPGDFFAR1 | |
| SCHEMBL12058190 | 0.89 | NPC1 (0.48) | NPC1RAB9ALMNAHPGDFFAR1 | |
| SCHEMBL13922023 | 0.88 | NPC1 (0.47) | NPC1RAB9ALMNAHPGDFFAR1 | |
| SCHEMBL21693343 | 0.85 | RAB9A (0.66) | NPC1RAB9ALMNAHPGDALDH1A1 | |
| SCHEMBL490778 | 0.82 | NPC1 (0.43) | NPC1RAB9ALMNAHPGDFFAR1 | |
| SCHEMBL10089270 | 0.81 | NPC1 (0.41) | NPC1RAB9ALMNAHPGDFFAR1 | |
| SCHEMBL9871889 | 0.80 | ALDH1A1 (0.62) | NPC1RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL1104224 | 0.79 | RAB9A (0.42) | NPC1RAB9ALMNAHPGDFFAR1 | |
| SCHEMBL13328499 | 0.74 | NPC1 (0.44) | NPC1RAB9ALMNAHPGDFFAR1 | |
| SCHEMBL8019089 | 0.70 | ALDH1A1 (0.50) | NPC1RAB9ALMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7316142-A | — | — | None | — | — | JP | disclosed |
| US-8377624-B2 | Negative-working thermal imageable elements | EASTMAN KODAK COMPANY (US) | 2013-02-19 | — | — | US | disclosed |
| US-8377624-B2 | Negative-working thermal imageable elements | EASTMAN KODAK COMPANY (US) | 2013-02-19 | — | — | US | disclosed |
| US-20100248097-A1 | NEGATIVE-WORKING THERMAL IMAGEABLE ELEMENTS | QUALEX INC. | 2010-09-30 | — | — | US | disclosed |
| US-20100248097-A1 | NEGATIVE-WORKING THERMAL IMAGEABLE ELEMENTS | QUALEX INC. | 2010-09-30 | — | — | US | disclosed |
| JP-H07316142-A | THIADIAZOLE DERIVATIVE | NIPPON OIL & FATS CO LTD | 1995-12-05 | — | — | JP | disclosed |