Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 11/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4907904 | 1.00 | PPARG (0.45) | PPARGPPARAACHEFAAHBCHE | |
| SCHEMBL13720973 | 0.88 | ALOX5 (0.41) | PPARGPPARAFAAHMEN1ALDH1A1 | |
| SCHEMBL14281847 | 0.88 | HIF1A (0.41) | PPARGPPARAACHEBCHEMEN1 | |
| SCHEMBL14307180 | 0.84 | PPARG (0.42) | PPARGPPARAACHEFAAHBCHE | |
| SCHEMBL4905528 | 0.84 | PPARG (0.43) | PPARGPPARAACHEFAAHBCHE | |
| SCHEMBL13899564 | 0.82 | PPARG (0.47) | PPARGPPARAACHEFAAHBCHE | |
| SCHEMBL14281860 | 0.81 | PPARG (0.36) | PPARGPPARAACHEFAAHBCHE | |
| SCHEMBL4779389 | 0.81 | PPARG (0.37) | PPARGPPARAACHEFAAHBCHE | |
| SCHEMBL4908590 | 0.81 | PPARG (0.37) | PPARGPPARAACHEFAAHBCHE | |
| SCHEMBL10184611 | 0.81 | ESR1 (0.41) | PPARGPPARAMAPTESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080009534-A1 | SUBSTITUTED ACID DERIVATIVES USEFUL AS ANTIDIABETIC AND ANTIOBESITY AGENTS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009534-A1 | SUBSTITUTED ACID DERIVATIVES USEFUL AS ANTIDIABETIC AND ANTIOBESITY AGENTS AND METHOD | GPR119, LIPC, CEL | PPARG 205/4885PPARA 133/4885ACHE 3926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.