Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA3 | P07451 | 1/20 | 0.71 |
| ▸ | CA4 | P22748 | 1/20 | 0.71 |
| ▸ | CA6 | P23280 | 1/20 | 0.71 |
| ▸ | MAOB | P27338 | 1/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.71 |
| ▸ | CA7 | P43166 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239117 | 0.98 | LMNA (0.73) | LMNACA12CA1CA2CA3 | |
| SCHEMBL4916596 | 0.97 | LMNA (0.71) | LMNACA12CA1CA2CA3 | |
| Ammonia Solution, Strong SCHEMBL3237966 | 0.97 | LMNA (0.71) | LMNACA12CA1CA2CA3 | |
| Water SCHEMBL3264442 | 0.97 | LMNA (0.71) | LMNACA12CA1CA2CA3 | |
| SCHEMBL4913871 | 0.88 | LMNA (0.60) | LMNACA12CA1CA2CA3 | |
| Zonisamide SCHEMBL1321446 | 0.85 | LMNA (0.97) | LMNACA12CA1CA2CA3 | |
| SCHEMBL28155790 | 0.84 | LMNA (0.55) | LMNACA12CA1CA2CA3 | |
| Zonisamide SCHEMBL29358822 | 0.83 | LMNA (1.00) | LMNACA12CA1CA2CA3 | |
| Zonisamide SCHEMBL1816247 | 0.83 | LMNA (1.00) | LMNACA12CA1CA2CA3 | |
| Zonisamide SCHEMBL35458 | 0.83 | LMNA (1.00) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115770613-B | Molecular sieve catalyst and preparation method thereof | 江西省科学院应用化学研究所 | 2024-03-12 | — | — | CN | claimed |
| CN-115770613-A | Molecular sieve catalyst and preparation method thereof | 江西省科学院应用化学研究所 | 2023-03-10 | — | — | CN | claimed |
| WO-2007016209-A2 | PURE 1,2-BENZISOXAZOLE-3-METHANE-SULFONIC ACID SODIUM SALT AND PURIFICATION PROCESS | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-02-08 | — | — | WO | claimed |
| CN-115770613-B | Molecular sieve catalyst and preparation method thereof | 江西省科学院应用化学研究所 | 2024-03-12 | — | — | CN | disclosed |
| CN-115770613-A | Molecular sieve catalyst and preparation method thereof | 江西省科学院应用化学研究所 | 2023-03-10 | — | — | CN | disclosed |
| EP-1728786-B1 | ONE-POT PROCESS FOR PRODUCING 1,2-BENZISOXAZOLE-3-METHANESULFONAMIDE | SUMITOMO DAINIPPON PHARMA CO LTD (JP) | 2016-01-13 | — | — | EP | disclosed |
| CN-1934096-B | Single-pot preparation method of 1, 2-benzisoxazole-3-methyl sulfonamide | DAINIPPON SUMITOMO PHARMA CO | 2012-04-18 | — | — | CN | disclosed |
| US-20080081914-A1 | PROCESS FOR THE PREPARATION OF BENZO [D] ISOXAZOL-3-YL-METHANESULFONIC ACID AND THE INTERMEDIATES THEREOF | DIPHARMA S.P.A. (IT) | 2008-04-03 | — | — | US | disclosed |
| US-7291742-B2 | Process for the preparation of benzo [d] isoxazol-3-yl-methanesulfonic acid and the intermediates thereof | DIPHARMA S.P.A. (IT) | 2007-11-06 | — | — | US | disclosed |
| US-7262304-B2 | One-pot process for the preparation of 1,2-benzisoxazole-3-methanesulfonamide | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| CN-1934096-A | One-pot process for the preparation of 1,2-benzisoxazole-3-methanesulfonamide | DAINIPPON SUMITOMO PHARMA CO (JP) | 2007-03-21 | — | — | CN | disclosed |
| US-7081539-B2 | One-pot process for the preparation of 1,2-benzisoxazole-3-methanesulfonamide | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2006-07-25 | — | — | US | disclosed |
| US-20060135582-A1 | Process for the preparation of benzo [d] isoxazol-3-yl-methanesulfonic acid and the intermediates thereof | DIPHARMA S.P.A. (IT) | 2006-06-22 | — | — | US | disclosed |
| EP-1581508-A1 | A PROCESS FOR THE PREPARATION OF BENZO D ISOXAZOL-3-YL- METHANESULFONIC ACID AND THE INTERMEDIATES THEREOF | Dipharma S.p.A. (IT) | 2005-10-05 | — | — | EP | disclosed |
| US-20050215796-A1 | One-pot process for the preparation of 1,2-benzisoxazole-3-methanesulfonamide | Sumitomo Pharma Co., Ltd. (JP) | 2005-09-29 | — | — | US | disclosed |
| WO-2005044808-A1 | A PROCESS FOR THE MANUFACTURE OF ZONISAMIDE | WOCKHARDT LIMITED (IN) | 2005-05-19 | — | — | WO | disclosed |
| WO-2004063173-A1 | A PROCESS FOR THE PREPARATION OF BENZO[D]ISOXAZOL-3-YL-METHANESULFONIC ACID AND THE INTERMEDIATES THEREOF | DIPHARMA S.P.A. (IT) | 2004-07-29 | — | — | WO | disclosed |
| US-20040049053-A1 | Process for the prepartion of 1,2-benzisoxazole-3-acetic acid | MENDELOVICI MARIOARA (IL) | 2004-03-11 | — | — | US | disclosed |
| US-6677458-B2 | REACTING 4-HYDROXY-COUMARIN WITH HYDROXYL-AMINE IN THE PRESENCE OF A BASE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-01-13 | — | — | US | disclosed |
| US-20020183525-A1 | Process for the preparation of 1,2-benzisoxazole-3-acetic acid | TEVA PHARMACEUTICALS USA, INC. | 2002-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081914-A1 | PROCESS FOR THE PREPARATION OF BENZO [D] ISOXAZOL-3-YL-METHANESULFONIC ACID AND THE INTERMEDIATES THEREOF | GABRD, GABRA5, GABRA6 | LMNA 1596/4885CA12 933/4885CA1 229/4885 |
| US-20040049053-A1 | Process for the prepartion of 1,2-benzisoxazole-3-acetic acid | HAO2, CYP4X1, CYP2S1 | LMNA 1402/4885CA12 770/4885CA1 109/4885 |
| US-20020183525-A1 | Process for the preparation of 1,2-benzisoxazole-3-acetic acid | HAO2, CYP2S1, CYP4X1 | LMNA 2783/4885CA12 705/4885CA1 154/4885 |
| US-20060135582-A1 | Process for the preparation of benzo [d] isoxazol-3-yl-methanesulfonic acid and the intermediates thereof | GABRD, GABRA5, GABRA6 | LMNA 1596/4885CA12 933/4885CA1 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.