Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.36 |
| ▸ | WNT3A | P56704 | 5/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 6/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14432421 | 0.92 | ACHE (0.36) | ACHEHTR4CTNNB1WNT3AOXTR | |
| SCHEMBL4904517 | 0.92 | OXTR (0.37) | ACHEHTR4CTNNB1WNT3AOXTR | |
| SCHEMBL4904291 | 0.90 | ACHE (0.34) | ACHEHTR4CTNNB1WNT3AOXTR | |
| SCHEMBL4912067 | 0.90 | MAPK14 (0.37) | ACHEHTR4CTNNB1WNT3AOXTR | |
| SCHEMBL5242825 | 0.88 | OXTR (0.40) | OXTRMAPK14GHSRGPBAR1ACACB | |
| SCHEMBL4912289 | 0.87 | AR (0.41) | OXTRMAPK14GHSRGPBAR1ACACB | |
| SCHEMBL4911069 | 0.85 | OXTR (0.40) | OXTRMAPK14GHSRGPBAR1 | |
| SCHEMBL14258931 | 0.85 | OXTR (0.42) | OXTRMAPK14GHSRGPBAR1 | |
| SCHEMBL14258933 | 0.85 | OXTR (0.42) | OXTRMAPK14GHSRGPBAR1 | |
| SCHEMBL4911012 | 0.85 | OXTR (0.42) | OXTRMAPK14GHSRGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080076760-A1 | 2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION | WAKAMOTO PHARMACEUTICAL CO., LTD (JP) | 2008-03-27 | — | — | US | disclosed |
| EP-1820799-A1 | 2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION | Wakamoto Pharmaceutical Co., Ltd. (JP) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076760-A1 | 2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION | GABRA5, GABRA1, GABRB1 | ACHE 4657/4885HTR4 390/4885CTNNB1 906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.