Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL4910791 | 0.89 | TSHR (0.35) | TSHRZDHHC20ZDHHC2 | |
| SCHEMBL176022 | 0.88 | ZDHHC20 (0.41) | TSHRZDHHC20ZDHHC2ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL5487748 | 0.86 | ZDHHC20 (0.40) | TSHRZDHHC20ZDHHC2ALDH1A1MAPK1 | |
| Sulfuric Acid SCHEMBL27766767 | 0.80 | ZDHHC20 (0.36) | TSHRZDHHC20ZDHHC2ALDH1A1MAPK1 | |
| SCHEMBL27594490 | 0.78 | ZDHHC20 (0.47) | TSHRZDHHC20ZDHHC2ALDH1A1MAPK1 | |
| SCHEMBL9191360 | 0.76 | ZDHHC20 (0.37) | ZDHHC20ZDHHC2 | |
| Hydrochloric Acid SCHEMBL15271262 | 0.76 | ZDHHC20 (0.46) | TSHRZDHHC20ZDHHC2ALDH1A1MAPK1 | |
| SCHEMBL3379719 | 0.76 | TSHR (0.41) | TSHRZDHHC20ZDHHC2ALDH1A1MAPK1 | |
| Bromide SCHEMBL31071682 | 0.73 | ZDHHC20 (0.51) | TSHRTP53ZDHHC20ZDHHC2ALDH1A1 | |
| Bromide SCHEMBL31071683 | 0.73 | ZDHHC20 (0.51) | TSHRTP53ZDHHC20ZDHHC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150147369-A1 | Personal Care Compositions That Deposit Solid Hydrophilic Benefit Agents | PROCTER & GAMBLE (US) | 2015-05-28 | — | — | US | disclosed |
| US-20130259913-A1 | PARTICLES AND PARTICLE GAS SATURATED SOLUTION PROCESSES FOR MAKING SAME | THE PROCTER & GAMBLE COMPANY | 2013-10-03 | — | — | US | disclosed |
| WO-2012141946-A1 | PARTICLES AND PARTICLE GAS SATURATED SOLUTION PROCESSES FOR MAKING SAME | THE PROCTER & GAMBLE COMPANY (US) | 2012-10-18 | — | — | WO | disclosed |
| US-8263058-B2 | Personal care compositions that deposit hydrophilic benefit agents | THE PROCTER & GAMBLE COMPANY (US) | 2012-09-11 | — | — | US | disclosed |
| US-20080031845-A1 | Personal care compositions that deposit hydrophilic benefit agents | STELLA QING | 2008-02-07 | — | — | US | disclosed |
| US-20080033058-A1 | Personal care compositions that deposit hydrophilic benefit agents | STELLA QING | 2008-02-07 | — | — | US | disclosed |
| EP-1744816-A1 | PERSONAL CARE COMPOSITIONS THAT DEPOSIT HYDROPHILIC BENEFIT AGENTS | The Procter and Gamble Company (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-0660696-B2 | LIPSTICKS | PROCTER & GAMBLE (US) | 2007-01-10 | — | — | EP | disclosed |
| EP-1737421-A2 | PERSONAL CARE COMPOSITIONS THAT DEPOSIT HYDROPHILIC BENEFIT AGENTS | The Procter and Gamble Company (US) | 2007-01-03 | — | — | EP | disclosed |
| EP-1737423-A1 | PERSONAL CARE COMPOSITIONS THAT DEPOSIT SOLID HYDROPHILIC BENEFIT AGENTS | The Procter and Gamble Company (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005102011-A2 | PERSONAL CARE COMPOSITIONS THAT DEPOSIT HYDROPHILIC BENEFIT AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 2005-11-03 | — | — | WO | disclosed |
| US-20050239670-A1 | Personal care compositions that deposit hydrophilic benefit agents | THE PROCTER & GAMBLE COMPANY | 2005-10-27 | — | — | US | disclosed |
| US-20050238680-A1 | Personal care compositions that deposit hydrophilic benefit agents | PROCTER & GAMBLE COMPANY, THE | 2005-10-27 | — | — | US | disclosed |
| EP-0950392-B1 | Non-sweating lipsticks | PROCTER & GAMBLE (US) | 2004-12-29 | — | — | EP | disclosed |
| US-6325995-B1 | Lipsticks compositions containing association structures | THE PROCTER & GAMBLE COMPANY | 2001-12-04 | — | — | US | disclosed |
| EP-0725620-B1 | NON-SWEATING LIPSTICKS | PROCTER & GAMBLE (US) | 2001-03-14 | — | — | EP | disclosed |
| EP-0950392-A1 | Non-sweating lipsticks | THE PROCTER & GAMBLE COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |
| EP-0660696-B1 | LIPSTICKS | PROCTER & GAMBLE (US) | 1997-01-08 | — | — | EP | disclosed |
| EP-0725620-A1 | NON-SWEATING LIPSTICKS | THE PROCTER & GAMBLE COMPANY (US) | 1996-08-14 | — | — | EP | disclosed |
| WO-1995011000-A1 | NON-SWEATING LIPSTICKS | THE PROCTER & GAMBLE COMPANY (US) | 1995-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033058-A1 | Personal care compositions that deposit hydrophilic benefit agents | CUTA, DSG1, PLOD3 | TSHR 3774/4885TP53 383/4885ZDHHC20 227/4885 |
| US-20050239670-A1 | Personal care compositions that deposit hydrophilic benefit agents | CUTA, DSG1, PLOD3 | TSHR 3774/4885TP53 383/4885ZDHHC20 227/4885 |
| US-20080031845-A1 | Personal care compositions that deposit hydrophilic benefit agents | CUTA, HHAT, SGMS1 | TSHR 3192/4885TP53 689/4885ZDHHC20 30/4885 |
| US-20150147369-A1 | Personal Care Compositions That Deposit Solid Hydrophilic Benefit Agents | CUTA, LIPA, DSG1 | TSHR 2935/4885TP53 1376/4885ZDHHC20 51/4885 |
| US-20050238680-A1 | Personal care compositions that deposit hydrophilic benefit agents | CUTA, HHAT, SGMS1 | TSHR 3192/4885TP53 689/4885ZDHHC20 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.