Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.70 |
| ▸ | HPGD | P15428 | 7/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | ALPG | P10696 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | NEK2 | P51955 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909612 | 1.00 | PKM (0.79) | PKML3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL4909621 | 1.00 | PKM (0.79) | PKML3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL11761154 | 0.94 | PKM (0.76) | PKML3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL11761160 | 0.94 | PKM (0.76) | PKML3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL11757992 | 0.92 | PKM (0.78) | PKML3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL1248023 | 0.90 | PKM (0.76) | PKML3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL1248024 | 0.90 | PKM (0.76) | PKML3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL11744756 | 0.89 | PKM (0.74) | PKML3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL11744761 | 0.89 | PKM (0.74) | PKML3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL29289246 | 0.89 | PKM (0.74) | PKML3MBTL1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113528593-B | Method for preparing alpha-phenyl cinnamonitrile derivative based on mechanical ball milling-enzyme catalytic coupling technology | 浙江工业大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-113528593-A | Method for preparing alpha-phenylcinnamonitrile derivative based on mechanical ball milling-enzyme catalytic coupling technology | 浙江工业大学 | 2021-10-22 | — | — | CN | disclosed |
| EP-1791901-B1 | STABILIZATION OF ORGANIC MATERIALS | BASF SE (DE) | 2018-03-28 | — | — | EP | disclosed |
| US-20160207932-A1 | NOVEL TRICYCLIC CHIRAL COMPOUNDS AND THEIR USE IN ASYMMETRIC CATALYSIS | UNIV NANYANG TECH (SG) | 2016-07-21 | — | — | US | disclosed |
| US-9206090-B2 | Tricyclic chiral compounds and their use in asymmetric catalysis | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-12-08 | — | — | US | disclosed |
| US-9051448-B2 | Stabilization of organic materials | BASF SE (DE) | 2015-06-09 | — | — | US | disclosed |
| US-20110269972-A1 | NOVEL TRICYCLIC CHIRAL COMPOUNDS AND THEIR USE IN ASYMMETRIC CATALYSIS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2011-11-03 | — | — | US | disclosed |
| US-20080269382-A1 | Stabilization of Organic Materials | BASF SE (DE) | 2008-10-30 | — | — | US | disclosed |
| EP-1791901-A2 | STABILIZATION OF ORGANIC MATERIALS | Ciba SC Holding AG (CH) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006024611-A2 | STABILIZATION OF ORGANIC MATERIALS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269972-A1 | NOVEL TRICYCLIC CHIRAL COMPOUNDS AND THEIR USE IN ASYMMETRIC CATALYSIS | SCO2, CBR3, HCCS | PKM 4035/4885L3MBTL1 2437/4885ALDH1A1 3150/4885 |
| US-20160207932-A1 | NOVEL TRICYCLIC CHIRAL COMPOUNDS AND THEIR USE IN ASYMMETRIC CATALYSIS | COX6C, CBR3, CYCS | PKM 1784/4885L3MBTL1 925/4885ALDH1A1 4294/4885 |
| US-20080269382-A1 | Stabilization of Organic Materials | LPO, PPOX, HMOX1 | PKM 1313/4885L3MBTL1 837/4885ALDH1A1 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.