Sugi Predict

Sugi Predict / Compounds / SCHEMBL863274

SCHEMBL863274

SCHEMBL863274

Cc1ccc2c(c1)N(c1ccccc1)c1cc(N)c(C)cc1N2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 9/20 0.43
▸ KDM4E B2RXH2 6/20 0.43
▸ GNG2 P59768 2/20 0.43
▸ GNB1 P62873 2/20 0.43
▸ HSD17B10 Q99714 2/20 0.40
▸ MAPT P10636 4/20 0.36
▸ SMN1; SMN2 Q16637 4/20 0.36
▸ GAA P10253 3/20 0.36
▸ NPC1 O15118 3/20 0.36
▸ RAB9A P51151 3/20 0.36
▸ HPGD P15428 2/20 0.36
▸ MCL1 Q07820 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ ROS1 P08922 1/20 0.34
▸ CDK5 Q00535 1/20 0.34
▸ ACVR1 Q04771 1/20 0.34
▸ LRRK2 Q5S007 1/20 0.34
▸ CHRM1 P11229 1/20 0.34
▸ CYP1A2 P05177 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5134183 0.92 ALDH1A1 (0.43) ALDH1A1KDM4EGNG2GNB1HSD17B10
SCHEMBL114129 0.91 KDM4E (0.43) ALDH1A1KDM4EGNG2GNB1HSD17B10
Hydrochloric Acid SCHEMBL27752560 0.90 KDM4E (0.42) ALDH1A1KDM4EGNG2GNB1HSD17B10
Hydrochloric Acid SCHEMBL30431952 0.90 KDM4E (0.42) ALDH1A1KDM4EGNG2GNB1HSD17B10
Sulfuric Acid SCHEMBL4915014 0.85 KDM4E (0.41) ALDH1A1KDM4EGNG2GNB1HSD17B10
SCHEMBL10048542 0.84 APAF1 (0.41) ALDH1A1KDM4EGNG2GNB1MAPT
SCHEMBL13320813 0.84 ALDH1A1 (0.46) ALDH1A1KDM4EGNG2GNB1HSD17B10
SCHEMBL863067 0.81 GNG2 (0.40) ALDH1A1KDM4EGNG2GNB1MAPT
SCHEMBL10045054 0.81 S100B (0.46) ALDH1A1KDM4EGNG2GNB1HSD17B10
SCHEMBL2849004 0.79 GAA (0.40) ALDH1A1KDM4EGNG2GNB1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040700-B2 Method of producing polymeric phenazonium compounds CITIBANK, N.A. 2015-05-26 — — US disclosed
US-20140163198-A1 Method of Producing Polymeric Phenazonium Compounds MACDERMID ACUMEN, INC. (US) 2014-06-12 — — US disclosed
US-8735580-B2 Method of producing polymeric phenazonium compounds CITIBANK, N.A. 2014-05-27 — — US disclosed
US-8691987-B2 Method of producing polymeric phenazonium compounds CITIBANK, N.A. 2014-04-08 — — US disclosed
US-20120077956-A1 Method of Producing Polymeric Phenazonium Compounds CITIBANK, N.A. 2012-03-29 — — US disclosed
US-20120073981-A1 Method of Producing Polymeric Phenazonium Compounds CITIBANK, N.A. 2012-03-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120073981-A1 Method of Producing Polymeric Phenazonium Compounds NOX5, PRMT5, CHRM5 ALDH1A1 2815/4885KDM4E 1175/4885GNG2 2135/4885
US-20140163198-A1 Method of Producing Polymeric Phenazonium Compounds NOX5, PRMT5, H1-5 ALDH1A1 2671/4885KDM4E 1276/4885GNG2 2408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.