Urea

Urea

SCHEMBL4916163

NC(N)=O.O=C(O)CCCCC(=O)ON1C(=O)CCC1=O.OCCO

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.36
FFAR1 O14842 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
CAMK2A Q9UQM7 1/20 0.34
LMNA P02545 3/20 0.33
TSHR P16473 2/20 0.33
PSMB8 P28062 1/20 0.33
PSMB5 P28074 1/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
GAA P10253 1/20 0.33
NFKB1 P19838 2/20 0.32
CYP2D6 P10635 1/20 0.32
PMP22 Q01453 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PTGS1 P23219 4/20 0.32
PTGS2 P35354 4/20 0.32
BLM P54132 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL4905652 0.97 TSHR (0.37) GPR84FFAR1FFAR4CAMK2ATSHR
Ethylene Glycol SCHEMBL28342229 0.94 GPR84 (0.42) GPR84FFAR1FFAR4CAMK2ALMNA
Ethylene Glycol SCHEMBL28881509 0.94 GPR84 (0.42) GPR84FFAR1FFAR4CAMK2ALMNA
Ethylene Glycol SCHEMBL6129445 0.92 TSHR (0.40) GPR84FFAR1FFAR4CAMK2ALMNA
Urea SCHEMBL4909809 0.91 PSMB8 (0.34) PSMB8PSMB5
SCHEMBL290460 0.91 LMNA (0.41) GPR84FFAR1FFAR4LMNATSHR
SCHEMBL25408775 0.89 TSHR (0.43) GPR84FFAR1FFAR4LMNATSHR
SCHEMBL25406852 0.89 TSHR (0.43) GPR84FFAR1FFAR4LMNATSHR
SCHEMBL25408300 0.89 TSHR (0.43) GPR84FFAR1FFAR4LMNATSHR
SCHEMBL905403 0.89 TSHR (0.43) GPR84FFAR1FFAR4LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080159975-A1 Hair treatment composition, hair treatment agent and method for treating hair by using the same SUNBIO, INC. (KR) 2008-07-03 US claimed
EP-1938795-A2 Hair treatment composition, hair treatment agent and method for treating hair by using the same Sunbio, Inc. (KR) 2008-07-02 EP claimed
US-20080159975-A1 Hair treatment composition, hair treatment agent and method for treating hair by using the same SUNBIO, INC. (KR) 2008-07-03 US disclosed
EP-1938795-A2 Hair treatment composition, hair treatment agent and method for treating hair by using the same Sunbio, Inc. (KR) 2008-07-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080159975-A1 Hair treatment composition, hair treatment agent and method for treating hair by using the same KRT18, CUTA, KRTCAP2 GPR84 1613/4885FFAR1 2500/4885FFAR4 1526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.