Urea

Urea

SCHEMBL4905652

NC(N)=O.O=C(O)CCCC(=O)ON1C(=O)CCC1=O.OCCO

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
CAMK2A Q9UQM7 1/20 0.34
SLC22A6 Q4U2R8 1/20 0.33
PSMB8 P28062 1/20 0.33
PSMB5 P28074 1/20 0.33
GPR84 Q9NQS5 1/20 0.32
FFAR1 O14842 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL4916163 0.97 GPR84 (0.36) TSHRCAMK2APSMB8PSMB5GPR84
Ethylene Glycol SCHEMBL6129445 0.95 TSHR (0.40) TSHRCAMK2ASLC22A6PSMB8PSMB5
Ethylene Glycol SCHEMBL28342229 0.91 GPR84 (0.42) TSHRCAMK2ASLC22A6PSMB8PSMB5
Ethylene Glycol SCHEMBL28881509 0.91 GPR84 (0.42) TSHRCAMK2ASLC22A6PSMB8PSMB5
Urea SCHEMBL4909809 0.91 PSMB8 (0.34) PSMB8PSMB5
SCHEMBL34382 0.91 TSHR (0.44) TSHRCAMK2ASLC22A6PSMB8PSMB5
Ethylene Glycol SCHEMBL6523939 0.89 PSMB8 (0.34) TSHRPSMB8PSMB5KMT2A
Urethane SCHEMBL4904899 0.88 ALOX15 (0.38) TSHRPSMB8PSMB5MEN1GAA
SCHEMBL290460 0.87 LMNA (0.41) TSHRSLC22A6GPR84FFAR1FFAR4
SCHEMBL26665749 0.86 TSHR (0.38) TSHRSLC22A6PSMB8PSMB5MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080159975-A1 Hair treatment composition, hair treatment agent and method for treating hair by using the same SUNBIO, INC. (KR) 2008-07-03 US claimed
EP-1938795-A2 Hair treatment composition, hair treatment agent and method for treating hair by using the same Sunbio, Inc. (KR) 2008-07-02 EP claimed
US-20080159975-A1 Hair treatment composition, hair treatment agent and method for treating hair by using the same SUNBIO, INC. (KR) 2008-07-03 US disclosed
EP-1938795-A2 Hair treatment composition, hair treatment agent and method for treating hair by using the same Sunbio, Inc. (KR) 2008-07-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080159975-A1 Hair treatment composition, hair treatment agent and method for treating hair by using the same KRT18, CUTA, KRTCAP2 TSHR 3358/4885CAMK2A 3964/4885SLC22A6 1716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.