Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498051 | 0.82 | ALDH1A1 (0.50) | MAPTHPGDTP53MAOARAB9A | |
| SCHEMBL20997312 | 0.81 | MAPT (0.51) | MAPTRAB9APOLBHSD11B1ALDH1A1 | |
| SCHEMBL4916675 | 0.81 | KMT2A (0.53) | MAPTHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15131565 | 0.80 | MAPT (0.57) | MAPTHPGDNPC1TP53MAOA | |
| SCHEMBL8495439 | 0.73 | ATM (0.51) | MAPTHPGDNPC1TP53MAOA | |
| SCHEMBL8495437 | 0.73 | ATM (0.51) | MAPTHPGDNPC1TP53MAOA | |
| SCHEMBL4909796 | 0.73 | CYP3A4 (0.71) | MAPTHPGDTP53RAB9APOLB | |
| SCHEMBL9407829 | 0.72 | SMN1; SMN2 (0.77) | MAPTRAB9ASMN1; SMN2HSD11B1ALDH1A1 | |
| Anisindione SCHEMBL29688105 | 0.72 | RAB9A (1.00) | MAPTHPGDNPC1TP53MAOA | |
| Anisindione SCHEMBL49379 | 0.72 | RAB9A (1.00) | MAPTHPGDNPC1TP53MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852749-B1 | Pyrazolidinol compounds | A-VIRAL AS (NO) | 2005-02-08 | — | — | US | disclosed |