Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 5/20 | 0.43 |
| ▸ | HRH1 | P35367 | 5/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914576 | 0.92 | HSD17B10 (0.43) | FFAR1HSD17B10CHRM1HDAC8POLB | |
| SCHEMBL4917134 | 0.86 | FKBP1A (0.50) | FFAR1HDAC8SRD5A2POLBFFAR4 | |
| SCHEMBL4925531 | 0.86 | FFAR1 (0.50) | FFAR1HDAC8SRD5A2POLBFFAR4 | |
| SCHEMBL5130653 | 0.85 | HRH2 (0.48) | HSD17B10CHRM1HDAC8POLBL3MBTL1 | |
| SCHEMBL14115841 | 0.81 | AKT1 (0.42) | FFAR1HDAC8AKT1AKT2AKT3 | |
| SCHEMBL14021703 | 0.81 | AKT1 (0.42) | FFAR1HDAC8AKT1AKT2AKT3 | |
| Hydrochloric Acid SCHEMBL4597128 | 0.80 | AKT1 (0.41) | FFAR1HDAC8POLBAKT1AKT2 | |
| SCHEMBL27154397 | 0.80 | HSD17B10 (0.71) | HSD17B10CHRM1HDAC8AKT1AKT2 | |
| SCHEMBL11226904 | 0.80 | HSD17B10 (0.71) | HSD17B10CHRM1HDAC8AKT1AKT2 | |
| SCHEMBL7214004 | 0.80 | HSD17B10 (0.71) | HSD17B10CHRM1HDAC8AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080175795-A1 | Novel derivatives of amino acids for treatment of obesity and related disorders | BEXEL PHARMACEUTICALS, INC. | 2008-07-24 | — | — | US | claimed |
| US-20080175795-A1 | Novel derivatives of amino acids for treatment of obesity and related disorders | BEXEL PHARMACEUTICALS, INC. | 2008-07-24 | — | — | US | disclosed |
| US-20080175795-A1 | Novel derivatives of amino acids for treatment of obesity and related disorders | BEXEL PHARMACEUTICALS, INC. | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080175795-A1 | Novel derivatives of amino acids for treatment of obesity and related disorders | GPR119, AADAT, FABP4 | FFAR1 14/4885HSD17B10 477/4885CHRM1 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.