SCHEMBL4919741

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4936406	0.81	CYP11B2 (0.44)	CYP11B2CYP2A6ALDH1A1HPGDTSHR
	SCHEMBL4921058	0.80	ALDH1A1 (0.45)	PDE3BPDE3ACYP11B2CYP2A6ALDH1A1
	SCHEMBL14154904	0.78	CYP2A6 (0.42)	PDE3BPDE3ACYP2A6ALDH1A1HPGD
	SCHEMBL4910712	0.77	ALDH1A1 (0.43)	CYP11B2CYP2A6ALDH1A1HPGDKDM1A
	SCHEMBL4919967	0.74	CYP2A6 (0.47)	PDE3BPDE3ACYP11B2CYP2A6ALDH1A1
	SCHEMBL4923428	0.73	KIF11 (0.46)	CYP11B2CYP2A6ALDH1A1HPGDKDM1A
	SCHEMBL4918366	0.73	ALDH1A1 (0.40)	CYP11B2CYP2A6ALDH1A1HPGDPGR
	SCHEMBL4910488	0.70	AR (0.43)	CYP11B2CYP2A6ALDH1A1HPGDPGR
	SCHEMBL4922378	0.70	AR (0.43)	CYP11B2CYP2A6ALDH1A1HPGDPGR
	SCHEMBL6466743	0.69	CYP2A6 (0.44)	CYP11B2CYP2A6ALDH1A1HPGDPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.