SCHEMBL4928076

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4919982	0.88	ROCK1 (0.69)	ACKR3ROCK1CYP3A4MMP13ROCK2
	SCHEMBL4930312	0.87	ESRRG (0.74)	ESRRGACKR3ROCK1MMP13ROCK2
	SCHEMBL4928319	0.85	ROCK1 (0.70)	ESRRGACKR3ROCK1CYP3A4MAPK14
	SCHEMBL4925690	0.83	ACKR3 (0.57)	ESRRGACKR3ROCK1CYP3A4LMNA
	SCHEMBL4929840	0.82	ESRRG (0.56)	ESRRGACKR3ROCK1CYP3A4ROCK2
	SCHEMBL4929351	0.82	ACKR3 (0.58)	ESRRGACKR3ROCK1ROCK2PRKACA
	SCHEMBL4928176	0.82	ROCK2 (0.57)	ESRRGACKR3ROCK1CYP3A4MMP13
	SCHEMBL4929172	0.82	HDAC1 (0.59)	ESRRGACKR3ROCK1CYP3A4ROCK2
	SCHEMBL4932331	0.82	DYRK1A (0.59)	ESRRGACKR3ROCK1ROCK2HDAC3
	SCHEMBL4924579	0.81	HDAC3 (0.68)	ESRRGACKR3ROCK1MMP13SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.