Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5188628 | 0.89 | HTR2A (0.46) | ALDH1A1HSP90AA1HSP90B1PKMHTR2A | |
| SCHEMBL11146428 | 0.85 | HTR2A (0.43) | ALDH1A1HTR2AKEAP1SLC6A2SLC6A4 | |
| SCHEMBL3821433 | 0.82 | HTR2A (0.56) | HTR2AKEAP1 | |
| SCHEMBL4869623 | 0.79 | MPO (0.45) | ALDH1A1HSP90AA1HSP90B1PKMHTR2A | |
| SCHEMBL2089904 | 0.79 | KDM4E (0.53) | ALDH1A1KDM4EIDO1SLC6A2SLC6A4 | |
| SCHEMBL5156201 | 0.79 | SLC5A1 (0.41) | ALDH1A1HSP90AA1HSP90B1PKMHTR2A | |
| SCHEMBL27473436 | 0.79 | LMNA (0.44) | ALDH1A1HSP90AA1HSP90B1PKMHTR2A | |
| SCHEMBL8875929 | 0.79 | ALDH1A1 (0.41) | ALDH1A1SLC5A1SLC5A2KDM4EIDO1 | |
| SCHEMBL2564249 | 0.78 | TAAR1 (0.46) | ALDH1A1PKMHTR2AKEAP1IDO1 | |
| Hydrochloric Acid SCHEMBL27607292 | 0.78 | ALDH1A1 (0.51) | ALDH1A1PKMKDM4EIDO1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789375-B1 | PROCESS FOR THE PRODUCTION OF [2-(4-FLUORO-BENZYL)-PHENYL]-ACETIC ACID | JANSSEN PHARMACEUTICA NV (BE) | 2015-12-09 | — | — | EP | disclosed |
| EP-1789375-B1 | PROCESS FOR THE PRODUCTION OF [2-(4-FLUORO-BENZYL)-PHENYL]-ACETIC ACID | JANSSEN PHARMACEUTICA NV (BE) | 2015-12-09 | — | — | EP | disclosed |
| CN-100591652-C | Method for producing 2-(4-fluoro-benzyl)-phenyl-acetic acid | JANSSEN PHARMACEUTICA NV | 2010-02-24 | — | — | CN | disclosed |
| US-7470809-B2 | Process for the production of [2-(4-fluoro-benzyl)-phenyl]-acetic acid | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-12-30 | — | — | US | disclosed |
| US-7470809-B2 | Process for the production of [2-(4-fluoro-benzyl)-phenyl]-acetic acid | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-12-30 | — | — | US | disclosed |
| US-7470809-B2 | Process for the production of [2-(4-fluoro-benzyl)-phenyl]-acetic acid | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-12-30 | — | — | US | disclosed |
| US-20070213556-A1 | NOVEL PROCESS FOR THE PRODUCTION OF [2-(4-FLUORO-BENZYL)-PHENYL]-ACETIC ACID | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-09-13 | — | — | US | disclosed |
| US-20070213556-A1 | NOVEL PROCESS FOR THE PRODUCTION OF [2-(4-FLUORO-BENZYL)-PHENYL]-ACETIC ACID | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-09-13 | — | — | US | disclosed |
| US-20070213556-A1 | NOVEL PROCESS FOR THE PRODUCTION OF [2-(4-FLUORO-BENZYL)-PHENYL]-ACETIC ACID | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-09-13 | — | — | US | disclosed |
| CN-101006039-A | Method for producing 2-(4-fluoro-benzyl)-phenyl-acetic acid | JANSSEN PHARMACEUTICA NV (BE) | 2007-07-25 | — | — | CN | disclosed |
| EP-1789375-A1 | PROCESS FOR THE PRODUCTION OF ¬2-(4-FLUORO-BENZYL)-PHENYL|-ACETIC ACID | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006024630-A1 | PROCESS FOR THE PRODUCTION OF [2- (4-FLUORO-BENZYL) -PHENYL] -ACETIC ACID | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213556-A1 | NOVEL PROCESS FOR THE PRODUCTION OF [2-(4-FLUORO-BENZYL)-PHENYL]-ACETIC ACID | ADH1A, ADH1C, CA4 | ALDH1A1 15/4885HSP90AA1 2696/4885HSP90B1 4098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.